Evidence map›Paper›PMID 21625349›Full record

ArticleClinical lipidology2011

Caveolae and lipid trafficking in adipocytes.

Paul F Pilch, Tova Meshulam, Shiying Ding, Libin Liu

Open access · greenAbstract read
In one paragraph

Article in Clinical lipidology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 44 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Caveolae: Metabolic Platforms at the Crossroads of Health and Disease.International journal of molecular sciences · 2025
    Review
  5. Article
  6. Article
  7. Prospects and challenges of tissue-derived extracellular vesicles.Molecular therapy : the journal of the American Society of Gene Therapy · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. EHD2-mediated restriction of caveolar dynamics regulates cellular fatty acid uptake.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  17. Lessons from cavin-1 deficiency.Biochemical Society transactions · 2020
    Review
  18. Energy and Dynamics of Caveolae Trafficking.Frontiers in cell and developmental biology · 2020
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Paul F PilchDepartment of Biochemistry, Boston University School of Medicine, 715 Albany St, Boston, MA 2118, USA.
Tova Meshulam
Shiying Ding
Libin Liu
Boston University · US

Funding

ACTIVATION OF HEXOSE TRANSPORT BY INSULINR01DK030425 · NIDDK · BOSTON UNIVERSITY MEDICAL CAMPUS · PI PILCH, PAUL F · 1986 to 2012
$3.5M
Role of Caveolae in Signaling in Fat CellsR01DK056935 · NIDDK · BOSTON UNIVERSITY MEDICAL CAMPUS · PI PILCH, PAUL F · 2001 to 2010
$2.6M
NIDDK NIH HHS R01 DK030425NIDDK NIH HHS R01 DK056935
6 · The paper itself

Abstract

The abundance of caveolae in adipocytes suggests a possible cell-specific role for these structures, and because these cells take up and release fatty acids as their quantitatively most robust activity, modulation of fatty acid movement is one such role that is supported by substantial in vitro and in vivo data. In addition, caveolae are particularly rich in cholesterol and sphingolipids, and indeed, fat cells harbor more cholesterol than any other tissue. In this article, we review the role of adipocyte caveolae with regard to these important lipid classes.

Identifiers

PMID21625349
PMCPMC3103140
OpenAlexW1963876085

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.