ArticleInfection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases2011
Genetic diversity of Plasmodium vivax malaria in China and Myanmar.
Article in Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Severe vivax malaria: a systematic review and meta-analysis of clinical studies since 1900.Malaria journal · 2014Pooled it
- Genetic diversity of Plasmodium vivax populations from the China-Myanmar border identified by genotyping merozoite surface protein markers.Tropical medicine and health · 2023Article
- PvMSP-3α and PvMSP-3β genotyping reveals higher genetic diversity in Plasmodium vivax parasites from migrant workers than residents at the China-Myanmar border.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2022Article
- Reconstruction ofInternational journal of molecular epidemiology and genetics · 2021Article
- Plasmodium vivax severe imported malaria in two migrants in France.Malaria journal · 2019Article
- Molecular approaches to determine the multiplicity of Plasmodium infections.Malaria journal · 2018Review
- Genetic Diversity and Natural Selection in 42 kDa Region of Plasmodium vivax Merozoite Surface Protein-1 from China-Myanmar Endemic Border.The Korean journal of parasitology · 2017Article
- Genetic diversity of Plasmodium Vivax revealed by the merozoite surface protein-1 icb5-6 fragment.Infectious diseases of poverty · 2017Article
- Spatiotemporal epidemic characteristics and risk factor analysis of malaria in Yunnan Province, China.BMC public health · 2017Article
- Assessment of an automated capillary system for Plasmodium vivax microsatellite genotyping.Malaria journal · 2015Article
- Genetic diversity of Plasmodium vivax in clinical isolates from Bangladesh.Malaria journal · 2015Article
- Genetic diversity of Plasmodium vivax population before elimination of malaria in Hainan Province, China.Malaria journal · 2015Article
- Genetic diversity of Plasmodium Vivax in South of Iran: A cross-sectional study.Journal of medicine and life · 2015Article
- The Plasmodium vivax merozoite surface protein 3β sequence reveals contrasting parasite populations in southern and northwestern Thailand.PLoS neglected tropical diseases · 2014Article
- PCR/RFLP-based analysis of genetically distinct Plasmodium vivax population of Pvmsp-3α and Pvmsp-3β genes in Pakistan.Malaria journal · 2014Article
- Genetic diversity and population structure of Plasmodium vivax in Central China.Malaria journal · 2014Article
- Genetic diversity of Plasmodium vivax population in Anhui province of China.Malaria journal · 2014Article
- Genotyping Plasmodium vivax isolates from the 2011 outbreak in Greece.Malaria journal · 2013Article
- Merozoite surface protein-3 alpha as a genetic marker for epidemiologic studies in Plasmodium vivax: a cautionary note.Malaria journal · 2013Article
- Plasmodium vivax isolates from Cambodia and Thailand show high genetic complexity and distinct patterns of P. vivax multidrug resistance gene 1 (pvmdr1) polymorphisms.The American journal of tropical medicine and hygiene · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
Abstract
Genetic diversity and population structure of Plasmodium vivax parasites are valuable to the prediction of the origin and spread of novel variants within and between populations, and to the program evaluation of malaria control measures. Using two polymorphic genetic markers, the merozoite surface protein genes PvMSP-3α and PvMSP-3β, we investigated the genetic diversity of four Southeast Asian P. vivax populations, representing both subtropical and temperate strains with dramatically divergent relapse patterns. PCR amplification of PvMSP-3α and PvMSP-3β genes detected three and four major size polymorphisms among the 235 infections examined, respectively, while restriction analysis detected 15 and 19 alleles, respectively. Samples from different geographical areas differed dramatically in their PvMSP-3α and PvMSP-3β allele composition and frequency. Samples tended to cluster on the basis of their PCR-RFLP polymorphism. These results indicated that different parasite genotypes were circulating in each endemic area, and that geographic isolation may exist. Multiple infections were detected in all four parasite populations, ranging from 20.5% to 31.8%, strongly indicating that P. vivax populations were highly diverse and multiple clonal infections are common in these malaria-hypoendemic regions of Southeast Asia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.