Evidence map›Paper›PMID 21624140›Full record

ArticleClinical and molecular allergy : CMA2011

Chronic granulomatous disease: a review of the infectious and inflammatory complications.

Eunkyung Song, Gayatri Bala Jaishankar, Hana Saleh, Warit Jithpratuck, Ryan Sahni, Guha Krishnaswamy

Open access · goldAbstract read
In one paragraph

Article in Clinical and molecular allergy : CMA, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

82 citing papers in PubMed, 168 citations in OpenAlex.

  1. Review
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  6. Targeting neutrophils for cancer therapy.Nature reviews. Drug discovery · 2025
    Review
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  8. Review
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  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Disseminated Pulmonary Mycosis Caused byCase reports in pediatrics · 2022
    Article
  17. International journal of clinical practice · 2022
    Review
  18. Article
  19. Article
  20. Article

22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Eunkyung SongDepartment of Pediatrics, Division of Allergy and Clinical Immunology, Quillen College of Medicine, East Tennessee State University, USA. krishnas@etsu.edu.
Gayatri Bala Jaishankar
Hana Saleh
Warit Jithpratuck
Ryan Sahni
Guha Krishnaswamy
East Tennessee State University · USJames H. Quillen VA Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic Granulomatous Disease is the most commonly encountered immunodeficiency involving the phagocyte, and is characterized by repeated infections with bacterial and fungal pathogens, as well as the formation of granulomas in tissue. The disease is the result of a disorder of the NADPH oxidase system, culminating in an inability of the phagocyte to generate superoxide, leading to the defective killing of pathogenic organisms. This can lead to infections with Staphylococcus aureus, Psedomonas species, Nocardia species, and fungi (such as Aspergillus species and Candida albicans). Involvement of vital or large organs can contribute to morbidity and/or mortality in the affected patients. Major advances have occurred in the diagnosis and treatment of this disease, with the potential for gene therapy or stem cell transplantation looming on the horizon.

Identifiers

PMID21624140
PMCPMC3128843
OpenAlexW2095972155

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.