Evidence map›Paper›PMID 21623544›Full record

ArticlePsychology & health2012

Perceived stress in prodromal Huntington disease.

Nancy Downing, Megan M Smith, Leigh J Beglinger, James Mills, Kevin Duff, Kelly C Rowe, Eric Epping, Jane S Paulsen, PREDICT-HD Investigators of Huntington Study Group

Abstract readComparative Study
In one paragraph

Article in Psychology & health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Article
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  9. Review
  10. Article
  11. Depression in the early stages of Huntington disease.Neurodegenerative disease management · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Nancy DowningCollege of Nursing, University of Iowa, Iowa City, IA 52242, USA.
Megan M Smith
Leigh J Beglinger
James Mills
Kevin Duff
Kelly C Rowe
Eric Epping
Jane S Paulsen
PREDICT-HD Investigators of Huntington Study Group
University of Iowa · USUniversity of Utah · US

Funding

NEUROBIOLOGICAL PREDICTORS OF HUNTINGTON'S DISEASER01NS040068 · NINDS · UNIVERSITY OF IOWA · PI PAULSEN, JANE S · 2001 to 2013
$48.5M
NINDS NIH HHS NS40068NINDS NIH HHS R01 NS040068
6 · The paper itself

Abstract

This study examines perceived stress and its relationship to depressive symptoms, life changes and functional capacity in a large sample of individuals who are positive for the Huntington disease (HD) gene expansion but not yet diagnosed. Participants were classified by estimated proximity to HD diagnosis (far, mid, near) and compared with a non-gene-expanded comparison group. Persons in the mid group had the highest stress scores. A significant interaction between age and time since HD genetic testing was also found. Secondary analyses using data from a different data collection point and including a diagnosed group showed the highest stress scores in the diagnosed group. Possible explanations and implications are discussed.

Indexed as

AdultDepressionFemaleGenetic Predisposition to DiseaseHumansHuntington DiseaseLongitudinal StudiesMaleMiddle AgedSelf ReportStress, PsychologicalYoung Adult

Identifiers

PMID21623544
PMCPMC3165107
OpenAlexW1964944371

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.