Evidence map›Paper›PMID 21623418›Full record

ReviewAmerican journal of orthopedics (Belle Mead, N.J.)2010

Remodeling and repair of orthopedic tissue: role of mechanical loading and biologics.

Spencer E Szczesny, Chang Soo Lee, Louis J Soslowsky

Abstract readReview
In one paragraph

Review in American journal of orthopedics (Belle Mead, N.J.), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Mechanoepigenetic regulation of extracellular matrix homeostasis via Yap and Taz.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  4. Immune and repair responses in joint tissues and lymph nodes after knee arthroplasty surgery in mice.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2021
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Spencer E SzczesnyMcKay Orthopaedic Research Laboratory, Department of Orthopaedic Surgery, and Bioengineering Department, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, USA.
Chang Soo Lee
Louis J Soslowsky

Funding

Anisotropic and Nonlinear Structure-Function of Normal and Degenerate TendonR01AR055598 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI ELLIOTT, DAWN M, SOSLOWSKY, LOUIS J · 2008 to 2011
$1.2M
NIAMS NIH HHS R01 AR055598
6 · The paper itself

Abstract

Orthopedic tissues respond to mechanical loads to maintain normal homeostasis and in response to injury. As the body of work on this continues to grow, it is important to synthesize the recent studies across tissues and specialties with one another and with past studies. Hence, this review highlights the knowledge gained since 2000, with only few exceptions, concerning the effects of mechanical load and biologics on remodeling and repair of orthopedic tissue.

Indexed as

Biological ProductsBone and BonesBone RegenerationCartilage, ArticularFracture HealingHomeostasisHumansLigaments, ArticularMenisci, TibialStress, MechanicalTendon InjuriesTendonsTibial Meniscus InjuriesWeight-BearingBiological Products

Identifiers

PMID21623418
PMCPMC6237093

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.