Evidence map›Paper›PMID 21623387›Full record

ArticleAsian journal of andrology2011

TRP channels in prostate cancer: the good, the bad and the ugly?

Dimitra Gkika, Natalia Prevarskaya

Open access · goldAbstract read
In one paragraph

Article in Asian journal of andrology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
1.7field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 71 citations in OpenAlex.

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  10. Review
  11. Ion Channel Profiling in Prostate Cancer: Toward Cell Population-Specific Screening.Reviews of physiology, biochemistry and pharmacology · 2021
    Review
  12. Article
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  19. TRPM8 and prostate: a cold case?Pflugers Archiv : European journal of physiology · 2018
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Dimitra GkikaInserm U1003, Equipe labellisée par la Ligue Nationale contre le cancer, Villeneuve d'Ascq, France. dimitra.gkika@univ-lille1.fr
Natalia Prevarskaya
Inserm · FRLaboratoire de Physiologie Cellulaire

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During the last decade, transient receptor potential (TRP) channels emerge as key proteins in central mechanisms of the carcinogenesis such as cell proliferation, apoptosis and migration. Initial studies showed that expression profile of some TRP channels, notably TRP melastatin 8 (TRPM8), TRP vanilloid 6 (TRPV6),TRP canonical (TRPC6) and TRPV2, is changing during the development and the progression of prostate cancer towards the hormone-refractory stages. The link between the change in expression levels and the functional role of these channels in prostate cancer is step by step being elucidated. These recent advances are here described and discussed.

Indexed as

ApoptosisCell MovementCell ProliferationHumansMaleNeoplasm InvasivenessProstatic NeoplasmsTRPC Cation ChannelsTRPC Cation Channels

Identifiers

PMID21623387
PMCPMC3739589
OpenAlexW2071947898

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.