Evidence map›Paper›PMID 21622642›Full record

ArticleDatabase : the journal of biological databases and curation2011

Curation of characterized glycoside hydrolases of fungal origin.

Caitlin Murphy, Justin Powlowski, Min Wu, Greg Butler, Adrian Tsang

Open access · goldAbstract read
In one paragraph

Article in Database : the journal of biological databases and curation, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 102 citations in OpenAlex.

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  9. Secretome Analysis ofFrontiers in microbiology · 2022
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  11. Genomic Studies of White-Rot FungusJournal of fungi (Basel, Switzerland) · 2021
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  12. Review
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  14. Review
  15. Article
  16. Polyketide Derivatives in the Resistance ofFrontiers in plant science · 2021
    Article
  17. Article
  18. Article
  19. Frontiers in bioengineering and biotechnology · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Caitlin MurphyCentre for Structural and Functional Genomics, Concordia University, Montreal QC H4B 1R6, Canada.
Justin Powlowski
Min Wu
Greg Butler
Adrian Tsang
Concordia University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fungi produce a wide range of extracellular enzymes to break down plant cell walls, which are composed mainly of cellulose, lignin and hemicellulose. Among them are the glycoside hydrolases (GH), the largest and most diverse family of enzymes active on these substrates. To facilitate research and development of enzymes for the conversion of cell-wall polysaccharides into fermentable sugars, we have manually curated a comprehensive set of characterized fungal glycoside hydrolases. Characterized glycoside hydrolases were retrieved from protein and enzyme databases, as well as literature repositories. A total of 453 characterized glycoside hydrolases have been cataloged. They come from 131 different fungal species, most of which belong to the phylum Ascomycota. These enzymes represent 46 different GH activities and cover 44 of the 115 CAZy GH families. In addition to enzyme source and enzyme family, available biochemical properties such as temperature and pH optima, specific activity, kinetic parameters and substrate specificities were recorded. To simplify comparative studies, enzyme and species abbreviations have been standardized, Gene Ontology terms assigned and reference to supporting evidence provided. The annotated genes have been organized in a searchable, online database called mycoCLAP (Characterized Lignocellulose-Active Proteins of fungal origin). It is anticipated that this manually curated collection of biochemically characterized fungal proteins will be used to enhance functional annotation of novel GH genes. Database URL: http://mycoCLAP.fungalgenomics.ca/.

Indexed as

CellulaseDatabases, ProteinFungiGenes, FungalGlycoside HydrolasesMolecular Sequence AnnotationSpecies SpecificityCellulaseGlycoside Hydrolases

Identifiers

PMID21622642
PMCPMC3263737
OpenAlexW2141158585

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.