ReviewBMC medicine2011
A perspective on SIDS pathogenesis. the hypotheses: plausibility and evidence.
Review in BMC medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 45 citations in OpenAlex.
- Oronasal blood, intrathoracic petechiae and pulmonary hemorrhages differentiate prone separate-bed from bed-sharing SIDS cases.Forensic science, medicine, and pathology · 2026Article
- Global trends, projections, and inequalities in neonatal sudden infant death syndrome mortality attributable to risk factors from 1990 to 2021.Translational pediatrics · 2026Article
- A Narrative Overview of Fatal Myocarditis in Infant with Focus on Sudden Unexpected Death and Forensic Implications.Journal of clinical medicine · 2025Review
- Sudden Infant Death Syndrome (SIDS): State of the Art and Future Directions.International journal of medical sciences · 2024Review
- Handle with Care: A Narrative Review of Infant Safe Sleep Practices across Clinical Guidelines and Social Media to Reduce SIDS.Children (Basel, Switzerland) · 2023Review
- The Science (or Nonscience) of Research Into Sudden Infant Death Syndrome (SIDS).Frontiers in pediatrics · 2022Article
- Sudden infant death syndrome: Melatonin, serotonin, and CD34 factor as possible diagnostic markers and prophylactic targets.PloS one · 2021Article
- Prenatal intermittent hypoxia sensitizes the laryngeal chemoreflex, blocks serotoninergic shortening of the reflex, and reduces 5-HTExperimental neurology · 2020Article
- Electrocardiographic Assessment and Genetic Analysis in Neonates: a Current Topic of Discussion.Current cardiology reviews · 2019Review
- Infection: the neglected paradigm in SIDS research.Archives of disease in childhood · 2017Review
- SIDS-CDF hypothesis revisited: explaining hypoxia in SIDS.Upsala journal of medical sciences · 2016Article
- SIDS-CDF Hypothesis Revisited: Cause vs. Contributing Factors.Frontiers in neurology · 2016Article
- Gut Microbiota and Immunity: Possible Role in Sudden Infant Death Syndrome.Frontiers in immunology · 2015Review
- A New Theory to Explain the Underlying Pathogenetic Mechanism of Sudden Infant Death Syndrome.Frontiers in neurology · 2015Review
- Escherichia coli and Sudden Infant Death Syndrome.Frontiers in immunology · 2015Review
- Hypophosphatemia and sudden infant death syndrome (SIDS)--is ATP the link?Upsala journal of medical sciences · 2014Article
- Inner ear insult ablates the arousal response to hypoxia and hypercarbia.Neuroscience · 2013Article
- Hypoxia at the heart of sudden infant death syndrome?Pediatric research · 2013Review
- Cardiorespiratory coupling in health and disease.Autonomic neuroscience : basic & clinical · 2013Review
- The SIDS--critical diaphragm failure hypothesis revisited.Upsala journal of medical sciences · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Several theories of the underlying mechanisms of Sudden Infant Death Syndrome (SIDS) have been proposed. These theories have born relatively narrow beach-head research programs attracting generous research funding sustained for many years at expense to the public purse. This perspective endeavors to critically examine the evidence and bases of these theories and determine their plausibility; and questions whether or not a safe and reasoned hypothesis lies at their foundation. The Opinion sets specific criteria by asking the following questions: 1. Does the hypothesis take into account the key pathological findings in SIDS? 2. Is the hypothesis congruent with the key epidemiological risk factors? 3. Does it link 1 and 2? Falling short of any one of these answers, by inference, would imply insufficient grounds for a sustainable hypothesis. Some of the hypotheses overlap, for instance, notional respiratory failure may encompass apnea, prone sleep position, and asphyxia which may be seen to be linked to co-sleeping. For the purposes of this paper, each element will be assessed on the above criteria.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.