Evidence map›Paper›PMID 21618591›Full record

ReviewJournal of cellular biochemistry2011

Regulation and function of axon guidance and adhesion molecules during olfactory map formation.

Gerald A Schwarting, Timothy R Henion

Open access · greenAbstract readReview
In one paragraph

Review in Journal of cellular biochemistry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Trans-Axonal Signaling in Neural Circuit Wiring.International journal of molecular sciences · 2020
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Gerald A SchwartingDepartment of Cell Biology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA. gerald.schwarting@umassmed.edu
Timothy R Henion
University of Massachusetts Chan Medical School · US

Funding

GLYCOCONJUGATES IN OLFACTORY CELL-CELL INTERACTIONSR01DC000953 · NIDCD · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI SCHWARTING, GERALD A · 1992 to 2011
$3.1M
Migration of early olfactory neuronal progenitorsR01DC009034 · NIDCD · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI SCHWARTING, GERALD A · 2007 to 2009
$906k
NIDCD NIH HHS R01 DC000953NIDCD NIH HHS R01 DC009034NIDCD NIH HHS R01-DC00953NIDCD NIH HHS R01-DC09034
6 · The paper itself

Abstract

The olfactory system presents a practical model for investigating basic mechanisms involved in patterning connections between peripheral sensory neurons and central targets. Our understanding of olfactory map formation was advanced greatly by the discovery of cAMP signaling as an important determinant of glomerular positioning in the olfactory bulb. Additionally, several cell adhesion molecules have been identified recently that are proposed to regulate homotypic interactions among projecting axons. From these studies a model has emerged to partially explain the wiring of axons from widely dispersed neuron populations in the nasal cavity to relatively stereotyped glomerular positions. These advances have revitalized interest in axon guidance molecules in establishing olfactory topography, but also open new questions regarding how these patterns of guidance cues are established and function, and what other pathways, such as glycosylation, might be involved. This review summarizes the current state of this field and the important molecules that impact on cAMP-dependent mechanism in olfactory axon guidance.

Indexed as

AnimalsAxonsCell Adhesion MoleculesHumansOlfactory BulbOlfactory PathwaysOlfactory Receptor NeuronsSignal TransductionCell Adhesion Molecules

Identifiers

PMID21618591
PMCPMC3376016
OpenAlexW2024816599

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.