Evidence map›Paper›PMID 21618003›Full record

ArticleJournal of molecular neuroscience : MN2011

What are the different initial presentations of frontotemporal dementia?

Tiffany W Chow

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of molecular neuroscience : MN, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Clinical Spectrum of Amyotrophic Lateral Sclerosis (ALS).Cold Spring Harbor perspectives in medicine · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Tiffany W ChowDepartment of Medicine, Division of Neurology, University of Toronto, Rotman Research Institute, 3560 Bathurst St, Toronto, ON, M6A 2E1, Canada. tchow@rotman-baycrest.on.ca

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Frontotemporal dementia (FTD) symptoms at the beginning of illness are in either the realm of behavioral disturbance or in language disruption, also known as aphasia. Based on specific constellations of behavioral change or characteristics of the aphasia, physicians can anticipate the type of protein that is abnormal in the brain. Family history rich with similar instances of illness can further guide the cause of illness in an individual. Knowing the type of protein abnormality (proteinopathy) from among the three most common in FTD (tau, TDP-43, or fused in sarcoma) can help treating clinicians to advise families on the future course of illness and future clinical drug trials that would be most applicable to each patient.

Indexed as

Diagnosis, DifferentialDNA-Binding ProteinsFrontotemporal DementiaHumansLanguagetau ProteinsDNA-Binding Proteinstau Proteins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.