ArticleFrontiers in integrative neuroscience2011
Spike rate and spike timing contributions to coding taste quality information in rat periphery.
Article in Frontiers in integrative neuroscience, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 27 citations in OpenAlex.
- Computational Advances in Taste Perception: From Ion Channels and Taste Receptors to Neural Coding.Brain sciences · 2025Article
- Unsupervised Bayesian Ising Approximation for decoding neural activity and other biological dictionaries.eLife · 2022Article
- Precise timing is ubiquitous, consistent, and coordinated across a comprehensive, spike-resolved flight motor program.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Recognizing Taste: Coding Patterns Along the Neural Axis in Mammals.Chemical senses · 2019Review
- Millisecond-scale motor encoding in a cortical vocal area.PLoS biology · 2014Article
- Local field potentials in the gustatory cortex carry taste information.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Incoordination between spikes and LFPs in Aβ1-42-mediated memory deficits in rats.Frontiers in behavioral neuroscience · 2014Article
- Brainstem stimulation augments information integration in the cerebral cortex of desflurane-anesthetized rats.Frontiers in integrative neuroscience · 2014Article
- Statistical analysis and decoding of neural activity in the rodent geniculate ganglion using a metric-based inference system.PloS one · 2013Article
- Acetic acid modulates spike rate and spike latency to salt in peripheral gustatory neurons of rats.Journal of neurophysiology · 2012Article
- Sensory receptor diversity establishes a peripheral population code for stimulus duration at low intensities.The Journal of experimental biology · 2012Article
- Anion size modulates salt taste in rats.Journal of neurophysiology · 2012Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
There is emerging evidence that individual sensory neurons in the rodent brain rely on temporal features of the discharge pattern to code differences in taste quality information. In contrast, investigations of individual sensory neurons in the periphery have focused on analysis of spike rate and mostly disregarded spike timing as a taste quality coding mechanism. The purpose of this work was to determine the contribution of spike timing to taste quality coding by rat geniculate ganglion neurons using computational methods that have been applied successfully in other systems. We recorded the discharge patterns of narrowly tuned and broadly tuned neurons in the rat geniculate ganglion to representatives of the five basic taste qualities. We used mutual information to determine significant responses and the van Rossum metric to characterize their temporal features. While our findings show that spike timing contributes a significant part of the message, spike rate contributes the largest portion of the message relayed by afferent neurons from rat fungiform taste buds to the brain. Thus, spike rate and spike timing together are more effective than spike rate alone in coding stimulus quality information to a single basic taste in the periphery for both narrowly tuned specialist and broadly tuned generalist neurons.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.