ReviewRadiation oncology (London, England)2011
Curative treatment of oesophageal carcinoma: current options and future developments.
Review in Radiation oncology (London, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Chemoradiotherapy versus chemoradiotherapy plus surgery for esophageal cancer.The Cochrane database of systematic reviews · 2017Pooled it
- The influence of dose distribution on treatment outcome in the SCOPE 1 oesophageal cancer trial.Radiation oncology (London, England) · 2016Trial
- Novel electrochemical platform based on CScientific reports · 2024Article
- Neoadjuvant versus definitive radiochemotherapy of locoregionally advanced oesophageal cancer-who benefits?Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2022Article
- Computed Tomography-Based Evaluation of Volume and Position Changes of the Target Region and Organs at Risk During Radiotherapy for Esophageal Cancer: A Pilot Study.Frontiers in oncology · 2021Article
- Rehabilitation strategies following oesophagogastric and Hepatopancreaticobiliary cancer (ReStOre II): a protocol for a randomized controlled trial.BMC cancer · 2020Article
- Computed tomography volumetry of esophageal cancer - the role of semiautomatic assessment.BMC medical imaging · 2019Article
- Low-dose spectral insufflation computed tomography protocol preoperatively optimized for T stage esophageal cancer - preliminary research experience.World journal of gastroenterology · 2018Observational
- Cellular and Molecular Mechanisms of 3,3'-Diindolylmethane in Gastrointestinal Cancer.International journal of molecular sciences · 2016Review
- Trends in esophageal cancer survival in United States adults from 1973 to 2009: A SEER database analysis.Journal of gastroenterology and hepatology · 2016Article
- Radiobiological determination of dose escalation and normal tissue toxicity in definitive chemoradiation therapy for esophageal cancer.International journal of radiation oncology, biology, physics · 2014Article
- Multimodality treatment of potentially curative gastric cancer: geographical variations and future prospects.World journal of gastroenterology · 2014Review
- Patterns of lymph node recurrence after radical surgery impacting on survival of patients with pT1-3N0M0 thoracic esophageal squamous cell carcinoma.Journal of Korean medical science · 2014Article
- Accuracy of multidetector-row CT for restaging after neoadjuvant treatment in patients with oesophageal cancer.European radiology · 2013Article
- Automated biological target volume delineation for radiotherapy treatment planning using FDG-PET/CT.Radiation oncology (London, England) · 2013Article
- Cyclin A overexpression is associated with chemosensitivity to paclitaxel-based chemotherapy in patients with esophageal squamous cell carcinoma.Oncology letters · 2012Article
- Comparison of ventilation and cardiovascular parameters between prone thoracoscopic and Ivor Lewis esophagectomy.Updates in surgery · 2012Article
- Treatment strategies for oesophageal cancer - time-trends and long term outcome data from a large tertiary referral centre.Radiation oncology (London, England) · 2012Article
- To Compare and Determine the Diagnostic Accuracy of [World journal of nuclear medicineArticle
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since the 1980s major advances in surgery, radiotherapy and chemotherapy have established multimodal approaches as curative treatment options for oesophageal cancer. In addition the introduction of functional imaging modalities such as PET-CT created new opportunities for a more adequate patient selection and therapy response assessment.The majority of oesophageal carcinomas are represented by two histologies: squamous cell carcinoma and adenocarcinoma. In recent years an epidemiological shift towards the latter was observed. From a surgical point of view, adenocarcinomas, which are usually located in the distal third of the oesophagus, may be treated with a transhiatal resection, whereas squamous cell carcinomas, which are typically found in the middle and the upper third, require a transthoracic approach. Since overall survival after surgery alone is poor, multimodality approaches have been developed. At least for patients with locally advanced tumors, surgery alone can no longer be advocated as routine treatment. Nowadays, scientific interest is focused on tumor response to induction radiochemotherapy. A neoadjuvant approach includes the early and accurate assessment of clinical response, optimally performed by repeated PET-CT imaging and endoscopic ultrasound, which may permit early adaption of the therapeutic concept. Patients with SCC that show clinical response by PET CT are considered to have a better prognosis, regardless of whether surgery will be performed or not. In non-responding patients salvage surgery improves survival, especially if complete resection is achieved.
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