Evidence map›Paper›PMID 21615638›Full record

ReviewHealth expectations : an international journal of public participation in health care and health policy2012

Close to the bench as well as at the bedside: involving service users in all phases of translational research.

Felicity Callard, Diana Rose, Til Wykes

Abstract readReview
In one paragraph

Review in Health expectations : an international journal of public participation in health care and health policy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Implementation research in Primary Care (Part 2): How to conduct implementation research?Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2026
    Review
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  7. Review
  8. Review
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  10. Translational pathology in drug discovery.Frontiers in pharmacology · 2024
    Article
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  15. Review
  16. Article
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  18. Article
  19. 'A limpet on a ship': Spatio-temporal dynamics of patient and public involvement in research.Health expectations : an international journal of public participation in health care and health policy · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Felicity CallardStakeholder Participation Theme, NIHR Biomedical Research Centre for Mental Health, South London and Maudsley NHS Foundation Trust and Institute of Psychiatry, King's College London, London,, UK. felicity.callard@kcl.ac.uk
Diana Rose
Til Wykes

Funding

Wellcome Trust 086049
6 · The paper itself

Abstract

aimThe paper aims to develop a model of translational research in which service user and other stakeholder involvement are central to each phase.

background'Translational' is the current medical buzzword: translational research has been termed 'bench to bedside' research and promises to fast-track biomedical advances in the service of patient benefit. Models usually conceive of translational research as a 'pipeline' that is divided into phases: the early phase is characterized as the province of basic scientists and laboratory-based clinical researchers; the later phases focus on the implementation, dissemination and diffusion of health applications. If service user involvement is mentioned, it is usually restricted to these later phases.

methodsThe paper critically reviews existing literature on translational research and medicine. The authors develop a theoretical argument that addresses why a reconceptualization of translational research is required on scientific, ethical and pragmatic grounds.

resultsThe authors reconceptualize the model of translational research as an interlocking loop rather than as a pipeline, one in which service user and other stakeholder involvement feed into each of its elements. The authors demonstrate that for the 'interlocking loop' model of translational research to be materialized in practice will require changes in how health research is structured and organized.

conclusionThe authors demonstrate the scientific, ethical and pragmatic benefits of involving service users in every phase of translational research. The authors' reconceptualized model of translational research contributes to theoretical and policy debates regarding both translational research and service user involvement.

Indexed as

Cooperative BehaviorBiomarkersClinical Trials as TopicHumansInformation DisseminationOrganizational InnovationPatient ParticipationResearch PersonnelTranslational Research, BiomedicalBiomarkers

Identifiers

PMID21615638
PMCPMC5060629

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.