Fluid resuscitation in acute illness--time to reappraise the basics.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

1. [Guidelines for diagnosis and treatment of liver failure (2024 version)].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025
   Guideline
2. Simplified severe sepsis protocol: a randomized controlled trial of modified early goal-directed therapy in Zambia.Critical care medicine · 2014
   Trial
3. When enough is enough: how the decision was made to stop the FEAST trial: data and safety monitoring in an African trial of Fluid Expansion As Supportive Therapy (FEAST) for critically ill children.Trials · 2013
   Trial
4. Rapid versus standard intravenous rehydration in paediatric gastroenteritis: pragmatic blinded randomised clinical trial.BMJ (Clinical research ed.) · 2011
   Trial
5. Venous excess ultrasonography (VExUS) captures dynamic changes in volume status surrounding hemodialysis: A multicenter prospective observational study.Research square · 2024
   Article
6. Mortality after emergency unit fluid bolus in febrile Ugandan children.PloS one · 2023
   Article
7. Medication and Fluid Management of Pediatric Sepsis and Septic Shock.Paediatric drugs · 2022
   Review
8. Normal saline bolus use in pediatric emergency departments is associated with poorer pain control in children with sickle cell anemia and vaso-occlusive pain.American journal of hematology · 2019
   Article
9. Endothelial Glycocalyx and Cardiopulmonary Bypass.The journal of extra-corporeal technology · 2017
   Review
10. Predicting mortality in sick African children: the FEAST Paediatric Emergency Triage (PET) Score.BMC medicine · 2015
    Article
11. Controversies in fluid therapy: Type, dose and toxicity.World journal of critical care medicine · 2014
    Review
12. Arterial pressure variations as parameters of brain perfusion in response to central blood volume depletion and repletion.Frontiers in physiology · 2014
    Article
13. Fluid balance and cardiac function in septic shock as predictors of hospital mortality.Critical care (London, England) · 2013
    Article
14. [Emergency treatment and management of anaphylaxis].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2013
    Review
15. 'The words will pass with the blowing wind': staff and parent views of the deferred consent process, with prior assent, used in an emergency fluids trial in two African hospitals.PloS one · 2013
    Article
16. Cardiac function in Ghanaian children with severe malaria.Intensive care medicine · 2012
    Article
17. The unrecognized effects of the volume and composition of the resuscitation fluid used during the administration of blood products.Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis · 2012
    Review
18. Early recognition and management of septic shock in children.Pediatric reports · 2012
    Article

Corrections and comments

• Comment on
  Mortality after fluid bolus in African children with severe infection.2011

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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