Evidence map›Paper›PMID 21615150›Full record

ReviewJournal of medicinal chemistry2011

Progress in structure based drug design for G protein-coupled receptors.

Miles Congreve, Christopher J Langmead, Jonathan S Mason, Fiona H Marshall

Abstract readReview
In one paragraph

Review in Journal of medicinal chemistry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed.

  1. A ComprehensiveAngewandte Chemie (International ed. in English) · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. The Effect of Deuteration on the HMolecules (Basel, Switzerland) · 2020
    Article
  8. Article
  9. X-Ray Crystallography and Free Energy Calculations Reveal the Binding Mechanism of AAngewandte Chemie (International ed. in English) · 2020
    Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Small-Molecule Patterning via Prefunctionalized Alkanethiols.Chemistry of materials : a publication of the American Chemical Society · 2018
    Article
  17. Review
  18. Review
  19. Article
  20. Article

20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Miles CongreveHeptares Therapeutics Limited, BioPark, Welwyn Garden City, Hertfordshire, UK. miles.congreve@heptares.com
Christopher J Langmead
Jonathan S Mason
Fiona H Marshall

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Drug DesignAllosteric RegulationAnimalsBinding SitesHumansLigandsModels, MolecularProtein ConformationReceptors, G-Protein-CoupledLigandsReceptors, G-Protein-Coupled

Identifiers

PMID21615150
PMCPMC3308205

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.