Evidence map›Paper›PMID 21614641›Full record

ArticleVeterinary research communications2011

Further insights into the characterization of equine adipose tissue-derived mesenchymal stem cells.

Oksana Raabe, Katja Shell, Antonia Würtz, Christine Maria Reich, Sabine Wenisch, Stefan Arnhold

Abstract read
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In one paragraph

Article in Veterinary research communications, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 42 citations in OpenAlex.

  1. Current and Emerging Biologic Therapies for Equine Tendon and Ligament Injuries.The Veterinary clinics of North America. Equine practice · 2025
    Review
  2. Article
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  9. Evaluation of adipose-derived stromal vascular fraction from the lateral tailhead, inguinal region, and mesentery of horses.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2016
    Article
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  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Oksana RaabeInstitute of Veterinary -Anatomy, -Histology and -Embryology, Justus-Liebig University of Giessen, Frankfurterstrasse, Germany, oksana.raabe@vetmed.uni-giessen.de
Katja Shell
Antonia Würtz
Christine Maria Reich
Sabine Wenisch
Stefan Arnhold
University of Giessen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adipose tissue-derived stem cells (ADSCs) represent a promising subpopulation of adult stem cells for tissue engineering applications in veterinary medicine. In this study we focused on the morphological and molecular biological properties of the ADSCs. The expression of stem cell markers Oct4, Nanog and the surface markers CD90 and CD105 were detected using RT-PCR. ADSCs showed a proliferative potential and were capable of adipogenic and osteogenic differentiation. Expression of Alkaline phosphatase (AP), phosphoprotein (SPP1), Runx2 and osteocalcin (OC) mRNA were positive in osteogenic lineages and peroxisome proliferator activated receptor (Pparγ2) mRNA was positive in adipogenic lineages. ADSCs show stem cell and surface marker profiles and differentiation characteristics that are similar to but distinct from other adult stem cells, such as bone marrow-derived mesenchymal stem cells (BM-MSCs). The availability of an easily accessible and reproducible cell source may greatly facilitate the development of stem cell based tissue engineering and therapies for regenerative equine medicine.

Indexed as

Cell DifferentiationAdipose TissueAdult Stem CellsAlkaline PhosphataseAnimalsAntigens, CDBiomarkersCells, CulturedCore Binding Factor Alpha 1 SubunitCytokinesDNA-Binding ProteinsHorsesMesenchymal Stem CellsOsteocalcinPPAR gammaReverse Transcriptase Polymerase Chain ReactionAlkaline PhosphataseAntigens, CDBiomarkersCore Binding Factor Alpha 1 SubunitCytokinesDNA-Binding ProteinsOsteocalcinPPAR gammaRNA, Messenger

Identifiers

PMID21614641
OpenAlexW1985061684

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.