ArticleWorld journal of urology2011
Identification of the prostate cancer index lesion by real-time elastography: considerations for focal therapy of prostate cancer.
Article in World journal of urology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 53 citations in OpenAlex.
- Shear-wave elastography: role in clinically significant prostate cancer with false-negative magnetic resonance imaging.European radiology · 2019Article
- Principles of ultrasound elastography.Abdominal radiology (New York) · 2018Review
- Multimodal Imaging in Focal Therapy Planning and Assessment in Primary Prostate Cancer.Clinical and translational imaging · 2017Article
- Supersonic transient magnetic resonance elastography for quantitative assessment of tissue elasticity.Physics in medicine and biology · 2017Article
- Article
- Identifying Clinically Significant Prostate Cancers using 3-D In Vivo Acoustic Radiation Force Impulse Imaging with Whole-Mount Histology Validation.Ultrasound in medicine & biology · 2016Article
- Innovations in diagnostic imaging of localized prostate cancer.World journal of urology · 2014Review
- Real-time elastography for the detection of prostate cancer.Current urology reports · 2014Review
- Real-time elastography of the prostate.BioMed research international · 2014Review
- [Transrectal ultrasound in prostate cancer patients: what can we really see?].Der Urologe. Ausg. A · 2013Article
- Image-guided robotic interventions for prostate cancer.Nature reviews. Urology · 2013Review
- Nutritional supplementation with L-arginine prevents pelvic radiation-induced changes in morphology, density, and regulating factors of blood vessels in the wall of rat bladder.World journal of urology · 2013Article
- [Imaging of the prostate].Der Urologe. Ausg. A · 2013Article
- Prostate focused ultrasound focal therapy--imaging for the future.Nature reviews. Clinical oncology · 2012Review
- Focal therapy of prostate cancer: evidence-based analysis for modern selection criteria.Current urology reports · 2012Review
- Potentials and limitations of real-time elastography for prostate cancer detection: a whole-mount step section analysis.TheScientificWorldJournal · 2012Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionFocal therapy of prostate cancer is gaining more and more interest. One of the drawbacks of focal therapy of prostate cancer is the problem of correct identification of prostate cancer lesions. The aim of the study was to evaluate the ability of real-time elastography to correctly identify the prostate cancer index lesion. MATERIALS AND
methodsIn 32 patients, real-time elastography was performed the day before prostatectomy. During the examination, the location of the main lesion suspicious for prostate cancer was prospectively recorded. Moreover, the results of the randomized multicore biopsies were also used to predict the location of the index lesion. The preoperative elastography results, the biopsy results, and a combined use of elastography and biopsy results were then compared with the pathological results to calculate the diagnostic values for correct index lesion identification.
resultsWhen using real-time elastography alone to identify the prostate cancer index lesion, sensitivity, specificity, negative predictive value, positive predictive value, and accuracy were 58.8, 43.3, 54.1, 48.1, and 51.6%, respectively. Data from randomized biopsies alone achieved 67.8, 48.4, 56.8, 60.0, and 58.1%, respectively. The combination of elastography and biopsy data increased the values to, respectively, 84.9, 48.4, 61.9, 75.0, and 66.1%.
conclusionIn this study, real-time elastography alone did not allow to identify the prostate cancer index lesion with satisfactory reliability. The combination of real-time elastography and data from randomized 12 core biopsies allows promising ability to correctly identify the prostate cancer index lesion.
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