Evidence map›Paper›PMID 21614433›Full record

ArticleJournal of neurology2011

Physical inactivity in Parkinson's disease.

Marlies van Nimwegen, Arlène D Speelman, Esther J M Hofman-van Rossum, Sebastiaan Overeem, Dorly J H Deeg, George F Borm, Marleen H L van der Horst, Bastiaan R Bloem, Marten Munneke

2 registry-linked trialsOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neurology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 154 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
154citing papers in PubMed, 10 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03329833 naunknown statusnot on this mapstarted 2017, after this paper: background citation

Motivational Interviewing and Physical Activity Change in Parkinson's Disease

TypeinterventionalSponsorShirley Ryan AbilityLabRan2017 to 2021Enrolled44ConditionsParkinson DiseaseArmsMotivational Interviewing, Web-based application
NCT07522138 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Home-based Self-exercise in Patients With Parkinson's Disease: A Feasibility Study

TypeinterventionalSponsorSeoul National University HospitalRan2026 to 2027Enrolled15ConditionsHome Exercise Program, PD - Parkinson's Disease, Feasibility StudiesArmsHome-based self-exercise feedback program using video
3 · Its place in the literature

Who cites it

154 citing papers in PubMed, 10 syntheses or guidelines pooled it, 365 citations in OpenAlex.

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  8. Virtual reality for rehabilitation in Parkinson's disease.The Cochrane database of systematic reviews · 2016
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94 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Marlies van NimwegenDepartment of Neurology, Nijmegen Centre for Evidence Based Practice, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB, Nijmegen, The Netherlands. M.Munneke@neuro.umcn.nl
Arlène D Speelman
Esther J M Hofman-van Rossum
Sebastiaan Overeem
Dorly J H Deeg
George F Borm
Marleen H L van der Horst
Bastiaan R Bloem
Marten Munneke
Radboud University Nijmegen · NLRadboud University Medical Center · NLEMGO Institute for Health and Care Research · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with Parkinson's disease (PD) are likely to become physically inactive, because of their motor, mental, and emotional symptoms. However, specific studies on physical activity in PD are scarce, and results are conflicting. Here, we quantified daily physical activities in a large cohort of PD patients and another large cohort of matched controls. Moreover, we investigated the influence of disease-related factors on daily physical activities in PD patients. Daily physical activity data of PD patients (n = 699) were collected in the ParkinsonNet trial and of controls (n = 1,959) in the Longitudinal Aging Study Amsterdam (LASA); data were determined using the LAPAQ, a validated physical activity questionnaire. In addition, variables that may affect daily physical activities in PD were recorded, including motor symptoms, depression, disability in daily life, and comorbidity. Patients were physically less active; a reduction of 29% compared to controls (95% CI, 10-44%). Multivariate regression analyses demonstrated that greater disease severity, gait impairment, and greater disability in daily living were associated with less daily physical activity in PD (R (2) = 24%). In this large study, we show that PD patients are about one-third less active compared to controls. While disease severity, gait, and disability in daily living predicted part of the inactivity, a portion of the variance remained unexplained, suggesting that additional determinants may also affect daily physical activities in PD. Because physical inactivity has many adverse consequences, work is needed to develop safe and enjoyable exercise programs for patients with PD.

Indexed as

Activities of Daily LivingMotor ActivityAgedCohort StudiesComorbidityDisability EvaluationFemaleHumansMaleParkinson DiseaseSurveys and Questionnaires

Identifiers

PMID21614433
PMCPMC3225631
OpenAlexW2061731279

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.