SOX2 and CHD7 cooperatively regulate human disease genes.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

1. Genotranscriptomic meta-analysis of the CHD family chromatin remodelers in human cancers - initial evidence of an oncogenic role for CHD7.Molecular oncology · 2017
   Pooled it
2. Craniofacial Development Is Fine-Tuned by Sox2.Genes · 2023
   Review
3. SOX2 and SOX21 in Lung Epithelial Differentiation and Repair.International journal of molecular sciences · 2022
   Review
4. Advances in Chromodomain Helicase DNA-Binding (CHD) Proteins Regulating Stem Cell Differentiation and Human Diseases.Frontiers in cell and developmental biology · 2021
   Review
5. Reproductive endocrine phenotypes relating to CHD7 mutations in humans.American journal of medical genetics. Part C, Seminars in medical genetics · 2017
   Review
6. Sox2 acts as a rheostat of epithelial to mesenchymal transition during neural crest development.Frontiers in physiology · 2014
   Article
7. CHD7 deficiency in "Looper", a new mouse model of CHARGE syndrome, results in ossicle malformation, otosclerosis and hearing impairment.PloS one · 2014
   Article
8. The multiple roles for Sox2 in stem cell maintenance and tumorigenesis.Cellular signalling · 2013
   Review
9. New Genetic Insights into Congenital Heart Disease.Journal of clinical & experimental cardiology · 2012
   Article
10. Transcriptomic analysis of pluripotent stem cells: insights into health and disease.Genome medicine · 2011
    Article

Corrections and comments

• Comment on
  Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes.2011

Authors and funding

2 authors at 1 institution in 1 country.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as