Evidence map›Paper›PMID 21613643›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA

A method and knowledge base for automated inference of patient problems from structured data in an electronic medical record.

Adam Wright, Justine Pang, Joshua C Feblowitz, Francine L Maloney, Allison R Wilcox, Harley Z Ramelson, Louise I Schneider, David W Bates

Registry-linked trialAbstract readValidation Study
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02596087 (Improving Quality by Maintaining Accurate Problems in the Electronic Health Record), which is not on this map. Cited by 57 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02596087 nacompletednot on this map

Improving Quality by Maintaining Accurate Problems in the Electronic Health Record

TypeinterventionalSponsorBrigham and Women's HospitalRan2016Enrolled2,386ConditionsAsthma, Atrial Fibrillation, Chronic Obstructive Pulmonary Disease, Coronary Artery DiseaseArmsProblem List Suggestion
3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Validity of International Classification of Diseases Codes for Identifying Neuro-Ophthalmic Disease in Large Data Sets: A Systematic Review.Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society · 2020
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  9. Semi-supervised ROC analysis for reliable and streamlined evaluation of phenotyping algorithms.Journal of the American Medical Informatics Association : JAMIA · 2024
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  16. Impact of a problem-oriented view on clinical data retrieval.Journal of the American Medical Informatics Association : JAMIA · 2021
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  19. Characterizing outpatient problem list completeness and duplications in the electronic health record.Journal of the American Medical Informatics Association : JAMIA · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Adam WrightDepartment of General Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA. awright5@partners.org
Justine Pang
Joshua C Feblowitz
Francine L Maloney
Allison R Wilcox
Harley Z Ramelson
Louise I Schneider
David W Bates

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAccurate knowledge of a patient's medical problems is critical for clinical decision making, quality measurement, research, billing and clinical decision support. Common structured sources of problem information include the patient problem list and billing data; however, these sources are often inaccurate or incomplete.

objectiveTo develop and validate methods of automatically inferring patient problems from clinical and billing data, and to provide a knowledge base for inferring problems. STUDY DESIGN AND

methodsWe identified 17 target conditions and designed and validated a set of rules for identifying patient problems based on medications, laboratory results, billing codes, and vital signs. A panel of physicians provided input on a preliminary set of rules. Based on this input, we tested candidate rules on a sample of 100,000 patient records to assess their performance compared to gold standard manual chart review. The physician panel selected a final rule for each condition, which was validated on an independent sample of 100,000 records to assess its accuracy.

resultsSeventeen rules were developed for inferring patient problems. Analysis using a validation set of 100,000 randomly selected patients showed high sensitivity (range: 62.8-100.0%) and positive predictive value (range: 79.8-99.6%) for most rules. Overall, the inference rules performed better than using either the problem list or billing data alone.

conclusionWe developed and validated a set of rules for inferring patient problems. These rules have a variety of applications, including clinical decision support, care improvement, augmentation of the problem list, and identification of patients for research cohorts.

Indexed as

Electronic Health RecordsKnowledge BasesMedical Records, Problem-OrientedPatient Care ManagementAlgorithmsHumans

Identifiers

PMID21613643
PMCPMC3197992

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.