Trial reportThe American journal of clinical nutrition2011
Effects of weight loss on serum vitamin D in postmenopausal women.
Trial report in The American journal of clinical nutrition, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00470119 (Exercise Diet and Sex Hormones in Postmenopausal Women), which is not on this map. Cited by 65 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Exercise Diet and Sex Hormones in Postmenopausal Women (NEW)
Who cites it
65 citing papers in PubMed, 4 syntheses or guidelines pooled it, 114 citations in OpenAlex.
- Determinants and Effects of Vitamin D Supplementation in Postmenopausal Women: A Systematic Review.Nutrients · 2023Pooled it
- Does exercise affect bone mineral density and content when added to a calorie-restricted diet? A systematic review and meta-analysis of controlled clinical trials.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022Pooled it
- Body Mass Index, Vitamin D, and Type 2 Diabetes: A Systematic Review and Meta-Analysis.Nutrients · 2018Pooled it
- A systematic review of the interrelation between diet- and surgery-induced weight loss and vitamin D status.Nutrition research (New York, N.Y.) · 2017Pooled it
- Exercise without Weight Loss Prevents Seasonal Decline in Vitamin D Metabolites: The VitaDEx Randomized Controlled Trial.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Trial
- Association of Body Weight With Response to Vitamin D Supplementation and Metabolism.JAMA network open · 2023Trial
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- Vitamin D supplementation in obese Sri Lankan children: a randomized controlled trial.BMC pediatrics · 2020Trial
- The effect of vitamin D supplementation in combination with low-calorie diet on anthropometric indices and androgen hormones in women with polycystic ovary syndrome: a double-blind, randomized, placebo-controlled trial.Journal of endocrinological investigation · 2018Trial
- Association between body weight and composition and plasma 25-hydroxyvitamin D level in the Diabetes Prevention Program.European journal of nutrition · 2017Trial
- Effect of Two-Year Caloric Restriction on Bone Metabolism and Bone Mineral Density in Non-Obese Younger Adults: A Randomized Clinical Trial.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2016Trial
- No effect of weight loss on LINE-1 methylation levels in peripheral blood leukocytes from postmenopausal overweight women.Obesity (Silver Spring, Md.) · 2014Trial
- Vitamin D3 supplementation during weight loss: a double-blind randomized controlled trial.The American journal of clinical nutrition · 2014Trial
- Association between subcutaneous white adipose tissue and serum 25-hydroxyvitamin D in overweight and obese adults.Nutrients · 2013Trial
- Influence of diet, exercise, and serum vitamin d on sarcopenia in postmenopausal women.Medicine and science in sports and exercise · 2013Trial
- Vitamin D supplementation and calcium absorption during caloric restriction: a randomized double-blind trial.The American journal of clinical nutrition · 2013Trial
- Self-monitoring and eating-related behaviors are associated with 12-month weight loss in postmenopausal overweight-to-obese women.Journal of the Academy of Nutrition and Dietetics · 2012Trial
- Effects of a caloric restriction weight loss diet and exercise on inflammatory biomarkers in overweight/obese postmenopausal women: a randomized controlled trial.Cancer research · 2012Trial
- Adoption of diet-related self-monitoring behaviors varies by race/ethnicity, education, and baseline binge eating score among overweight-to-obese postmenopausal women in a 12-month dietary weight loss intervention.Nutrition research (New York, N.Y.) · 2012Trial
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 1 institution in 2 countries.
Funding
Abstract
backgroundLow concentrations of circulating vitamin D are common with obesity and may represent a potential mechanism explaining the elevated risk of certain cancers and cardiovascular outcomes observed in individuals who are overweight or obese.
objectiveThe objective of this study was to investigate the effects of 12 mo of weight loss through caloric restriction, exercise intervention, or both on serum 25-hydroxyvitamin D [25(OH)D] concentrations.
designOverweight and obese postmenopausal women (n = 439) were randomly assigned to 1 of 4 groups: 1) diet modification (n = 118), 2) exercise (n = 117), 3) diet + exercise (n = 117), or 4) control (n = 87). The diet intervention was a group-based reduced-calorie program with a 10% weight-loss goal. The exercise intervention consisted of 45 min of moderate-to-vigorous intensity aerobic activity daily for 5 d/wk. Serum 25(OH)D concentrations were measured by using a competitive chemiluminescent immunoassay at baseline and 12 mo.
resultsNo significant change in serum 25(OH)D was found between the intervention and control groups. Women who lost <5%, 5-9.9%, 10-14.9%, or ≥15% of baseline weight had mean increases in 25(OH)D of 2.1, 2.7, 3.3, and 7.7 ng/mL, respectively (P for trend = 0.002). Baseline vitamin D status did not modify the effect of the interventions on weight loss or body-composition changes at the 12-mo follow-up.
conclusionA greater degree of weight loss, achieved through either a reduced-calorie diet or increased exercise, is associated with increased circulating 25(OH)D concentrations. This trial is registered at clinicaltrials.gov as NCT00470119.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.