Evidence map›Paper›PMID 21613435›Full record

ArticleJournal of clinical microbiology2011

Efficient direct extended-spectrum β-lactamase detection by multiplex real-time PCR: accurate assignment of phenotype by use of a limited set of genetic markers.

Justin Ellem, Sally R Partridge, Jonathan R Iredell

Abstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

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  8. Preponderance ofFrontiers in microbiology · 2021
    Article
  9. Molecular characterization ofNew microbes and new infections · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Justin EllemCIDM, Level 3 ICPMR Building, Westmead Hospital, Westmead NSW 2145, Australia.
Sally R Partridge
Jonathan R Iredell

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The number and diversity of genes potentially complicate genetic approaches to the rapid detection of transmissible extended-spectrum β-lactamase genes. We developed a robust multiplexed real-time PCR assay based on targets identified in a prior survey and used this to detect relevant genes in 617 consecutive clinical isolates of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae.

Indexed as

Genetic Markersbeta-LactamasesEnterobacteriaceaeEnterobacteriaceae InfectionsHumansMicrobial Sensitivity TestsMultiplex Polymerase Chain ReactionReal-Time Polymerase Chain Reactionbeta-LactamasesGenetic Markers

Identifiers

PMID21613435
PMCPMC3147779

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.