ArticleDevelopment (Cambridge, England)2011
dachsous and frizzled contribute separately to planar polarity in the Drosophila ventral epidermis.
Article in Development (Cambridge, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
34 citing papers in PubMed.
- Planar Cell Polarity Signaling: Coordinated Crosstalk for Cell Orientation.Journal of developmental biology · 2024Review
- Emerging Mechanisms of Growth and Patterning Regulation by Dachsous and Fat Protocadherins.Frontiers in cell and developmental biology · 2022Review
- How do the Fat-Dachsous and core planar polarity pathways act together and independently to coordinate polarized cell behaviours?Open biology · 2021Review
- Planar cell polarity in the larval epidermis ofOpen biology · 2020Article
- Importance of miRNA stability and alternative primary miRNA isoforms in gene regulation duringeLife · 2018Article
- The Drosophila homologue of MEGF8 is essential for early development.Scientific reports · 2018Article
- Atypical Cadherin Dachsous1b Interacts with Ttc28 and Aurora B to Control Microtubule Dynamics in Embryonic Cleavages.Developmental cell · 2018Article
- Big roles for Fat cadherins.Current opinion in cell biology · 2018Review
- Article
- A switch in the mode of Wnt signaling orchestrates the formation of germline stem cell differentiation niche in Drosophila.PLoS genetics · 2018Article
- An embryonic system to assess direct and indirect Wnt transcriptional targets.Scientific reports · 2017Article
- Scaling of cytoskeletal organization with cell size inMolecular biology of the cell · 2017Article
- Planar Cell Polarity Effector Fritz Interacts with Dishevelled and Has Multiple Functions in Regulating PCP.G3 (Bethesda, Md.) · 2017Article
- Centriole positioning in epithelial cells and its intimate relationship with planar cell polarity.BioEssays : news and reviews in molecular, cellular and developmental biology · 2016Review
- Review
- Planar cell polarity: the Dachsous/Fat system contributes differently to the embryonic and larval stages of Drosophila.Biology open · 2016Article
- Prickle isoforms control the direction of tissue polarity by microtubule independent and dependent mechanisms.Biology open · 2016Article
- Article
- Dachsous1b cadherin regulates actin and microtubule cytoskeleton during early zebrafish embryogenesis.Development (Cambridge, England) · 2015Article
- Spatial and temporal aspects of Wnt signaling and planar cell polarity during vertebrate embryonic development.Seminars in cell & developmental biology · 2015Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Cells that comprise tissues often need to coordinate cytoskeletal events to execute morphogenesis properly. For epithelial tissues, some of that coordination is accomplished by polarization of the cells within the plane of the epithelium. Two groups of genes--the Dachsous (Ds) and Frizzled (Fz) systems--play key roles in the establishment and maintenance of such polarity. There has been great progress in uncovering the how these genes work together to produce planar polarity, yet fundamental questions remain unanswered. Here, we study the Drosophila larval ventral epidermis to begin to address several of these questions. We show that ds and fz contribute independently to polarity and that they do so over spatially distinct domains. Furthermore, we find that the requirement for the Ds system changes as field size increases. Lastly, we find that Ds and its putative receptor Fat (Ft) are enriched in distinct patterns in the epithelium during embryonic development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.