ReviewJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research2011
Genome-scale techniques highlight the epigenome and redefine fundamental principles of gene regulation.
Review in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 18 citations in OpenAlex.
- Inhibition of EED enhances osteogenic differentiation and bone formation: a potential therapeutic strategy for osteogenesis imperfecta.JBMR plus · 2026Article
- Enhancer of Zeste Homolog 2 Inhibition Stimulates Bone Formation and Mitigates Bone Loss Caused by Ovariectomy in Skeletally Mature Mice.The Journal of biological chemistry · 2016Article
- Epigenetic Control of Skeletal Development by the Histone Methyltransferase Ezh2.The Journal of biological chemistry · 2015Article
- Osteocytes, not Osteoblasts or Lining Cells, are the Main Source of the RANKL Required for Osteoclast Formation in Remodeling Bone.PloS one · 2015Article
- Fundamentals of vitamin D hormone-regulated gene expression.The Journal of steroid biochemistry and molecular biology · 2014Review
- Identification of an enhancer that increases miR-200b~200a~429 gene expression in breast cancer cells.PloS one · 2013Article
- Regulation of mouse Cyp24a1 expression via promoter-proximal and downstream-distal enhancers highlights new concepts of 1,25-dihydroxyvitamin D(3) action.Archives of biochemistry and biophysics · 2012Article
- Regulation of target gene expression by the vitamin D receptor - an update on mechanisms.Reviews in endocrine & metabolic disorders · 2012Review
- The need for mouse models in osteoporosis genetics research.BoneKEy reports · 2012Article
- Genome-wide principles of gene regulation by the vitamin D receptor and its activating ligand.Molecular and cellular endocrinology · 2011Review
- PI3Kγ deletion reduces variability in the in vivo osteolytic response induced by orthopaedic wear particles.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The regulation of gene expression represents one of the most fundamental of biologic processes that controls cellular proliferation, differentiation, and function. Recent technological advances in genome-wide annotation together with bioinformatic/computational analyses have contributed significantly to our understanding of transcriptional regulation at the epigenomic and regulomic levels. This perspective outlines the techniques that are being utilized and summarizes a few of the outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.