ArticleMedical microbiology and immunology2011
Seroprevalence study in forestry workers of a non-endemic region in eastern Germany reveals infections by Tula and Dobrava-Belgrade hantaviruses.
Article in Medical microbiology and immunology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.
- Occupational Hantavirus Infections in Agricultural and Forestry Workers: A Systematic Review and Metanalysis.Viruses · 2021Pooled it
- Hantavirus seroprevalence and associated factors for exposure in south-central Uganda.Emerging microbes & infections · 2026Article
- Prevalence of antibodies against hantavirus, Leptospira, lymphocytic choriomeningitis virus and Chlamydia psittaci in pest control workers in Germany - a cross-sectional study.Journal of occupational medicine and toxicology (London, England) · 2026Article
- Lymphocytic Choriomeningitis Virus Seroprevalence in a Cohort of German Forestry Workers.Viruses · 2025Article
- Puumala orthohantavirus: prevalence, biology, disease, animal models and recent advances in therapeutics development and structural biology.Frontiers in immunology · 2025Review
- Investigation of Viral, Bacterial and Parasitic Zoonotic Diseases in Rodents in Turkey.Veterinary medicine and science · 2024Article
- Hantavirus antibody seroprevalence and risk factors among adults in West Kazakhstan, 2023.Frontiers in public health · 2024Article
- Characterization of a Panel of Cross-Reactive Hantavirus Nucleocapsid Protein-Specific Monoclonal Antibodies.Viruses · 2023Article
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- Hantaviruses in Agricultural and Forestry Workers: Knowledge, Attitudes and Practices in Italian Physicians.Tropical medicine and infectious disease · 2021Article
- Hantavirus infections in Italy: not reported doesn't mean inexistent.Acta bio-medica : Atenei Parmensis · 2021Article
- Spatial and Temporal Dynamics and Molecular Evolution ofViruses · 2021Article
- Tula Virus as Causative Agent of Hantavirus Disease in Immunocompetent Person, Germany.Emerging infectious diseases · 2021Article
- Development of a Comparative European Orthohantavirus Microneutralization Assay With Multi- Species Validation and Evaluation in a Human Diagnostic Cohort.Frontiers in cellular and infection microbiology · 2020Article
- Article
- Molecular evidence of Tula virus in Microtus obscurus in the region of Yili, Xinjiang, China.BMC infectious diseases · 2019Article
- Review
- Association of low serum TGF-β level in hantavirus infected patients with severe disease.BMC immunology · 2015Article
- Beech Fructification and Bank Vole Population Dynamics--Combined Analyses of Promoters of Human Puumala Virus Infections in Germany.PloS one · 2015Article
- Human seroprevalence indicating hantavirus infections in tropical rainforests of Côte d'Ivoire and Democratic Republic of Congo.Frontiers in microbiology · 2015Article
Corrections and comments
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Authors and funding
12 authors at 8 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Highly endemic and outbreak regions for human hantavirus infections are located in the southern, southeastern, and western parts of Germany. The dominant hantavirus is the bank vole transmitted Puumala virus (PUUV). In the eastern part of Germany, previous investigations revealed Tula virus (TULV) and Dobrava-Belgrade virus (DOBV) infections in the respective rodent reservoirs. Here, we describe a seroprevalence study in forestry workers from Brandenburg, eastern Germany, using IgG ELISA and immunoblot tests based on recombinant TULV, DOBV, and PUUV antigens. Out of the 563 sera tested, 499 from male and 64 from female workers, we found 41 out of the 499 (8.2%) sera from men (mean age 47 years) and 10 out of 64 (15.6%) from the women (mean age 48 years) anti-hantavirus-positive. The majority of the 51 seropositive samples reacted exclusively in the TULV (n=22) and DOBV tests (n=17). Focus reduction neutralization assay investigations on selected sera confirmed the presence of TULV- and DOBV-specific antibodies in the forestry workers. These investigations demonstrated a potential health threat for forestry workers and also the average population in non-endemic geographical regions where TULV and DOBV are circulating in the corresponding reservoir hosts. The infections in this region might be frequently overlooked due to their unspecific and mild symptoms.
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