ArticleEuropean journal of applied physiology2012
Muscle damage protection by low-intensity eccentric contractions remains for 2 weeks but not 3 weeks.
Article in European journal of applied physiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Effects of Pre-conditioning on Exercise-Induced Muscle Damage: A Systematic Review and Meta-analysis.Sports medicine (Auckland, N.Z.) · 2023Pooled it
- Jaboticaba berry (Myrciaria jaboticaba) consumption improves plasma GSH levels and accelerates muscle recovery following exercise-induced muscle damage: a randomized, placebo-controlled trial.European journal of nutrition · 2025Trial
- Effects of Eccentric Exercise of the Extensors on Eccentric Exercise-Induced Muscle Damage of the Flexors in Limbs.Medicine and science in sports and exercise · 2025Trial
- The effect of eccentric exercise with blood flow restriction on neuromuscular activation, microvascular oxygenation, and the repeated bout effect.European journal of applied physiology · 2017Trial
- Effect of eicosapentaenoic acids-rich fish oil supplementation on motor nerve function after eccentric contractions.Journal of the International Society of Sports Nutrition · 2017Trial
- Effect of two maximal isometric contractions on eccentric exercise-induced muscle damage of the elbow flexors.European journal of applied physiology · 2013Trial
- Ipsilateral Repeated Bout Effect Across Heterologous Muscle Groups: Eccentric Knee Extensor Conditioning Enhances Elbow Flexor Recovery in Young Women.Life (Basel, Switzerland) · 2025Article
- Biceps brachii elastography in well-trained men post eccentric exercise-induced muscle damage.Journal of ultrasound · 2025Article
- The acute and repeated bout effects of multi-joint eccentric exercise on physical function and balance in older adults.European journal of applied physiology · 2023Article
- Eccentric exercise causes delayed sensory nerve conduction velocity but no repeated bout effect in the flexor pollicis brevis muscles.European journal of applied physiology · 2021Article
- Short-term neuromuscular, morphological, and architectural responses to eccentric quasi-isometric muscle actions.European journal of applied physiology · 2021Article
- Exercise induced changes in echo intensity within the muscle: a brief review.Journal of ultrasound · 2020Review
- Damage protective effects conferred by low-intensity eccentric contractions on arm, leg and trunk muscles.European journal of applied physiology · 2019Article
- Preconditioning contractions prevent the delayed onset of myofibrillar dysfunction after damaging eccentric contractions.The Journal of physiology · 2018Article
- Effects of preconditioning hamstring resistance exercises on repeated sprinting-induced muscle damage in female soccer players.Biology of sport · 2018Article
- Prevention of downhill walking-induced muscle damage by non-damaging downhill walking.PloS one · 2017Article
- Superior Effects of Eccentric to Concentric Knee Extensor Resistance Training on Physical Fitness, Insulin Sensitivity and Lipid Profiles of Elderly Men.Frontiers in physiology · 2017Article
- Preconditioning by light-load eccentric exercise is equally effective as low-level laser therapy in attenuating exercise-induced muscle damage in collegiate men.Journal of pain research · 2017Article
- Influence of Maturation Status on Eccentric Exercise-Induced Muscle Damage and the Repeated Bout Effect in Females.Frontiers in physiology · 2017Article
- Differences in post-exercise T2 relaxation time changes between eccentric and concentric contractions of the elbow flexors.European journal of applied physiology · 2016Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study investigated the hypothesis that the protective effect conferred by a low-intensity eccentric exercise against maximal eccentric exercise would not last more than a week. Untrained men (21.3 ± 1.6 years) were allocated into either a control or one of four repeated bout groups (n = 13 per group). The repeated bout groups performed 30 low-intensity eccentric contractions (ECC) of the elbow flexors with a dumbbell set at 10% of maximal isometric strength (10%-ECC) either 2 days, 7 days (1 week), 14 days (2 weeks) or 21 days (3 weeks) before 30 maximal eccentric contractions (Max-ECC). The control group performed Max-ECC only. Changes in maximal voluntary contraction strength, optimum angle, range of motion, upper arm circumference, muscle soreness, plasma creatine kinase activity and myoglobin concentration, and ultrasound echo-intensity following 10%-ECC were analysed by a one-way repeated measures ANOVA. Changes in the variables following Max-ECC were compared among the groups by a two-way repeated measures ANOVA. The 10%-ECC did not change any variables, showing no indication of muscle damage. The changes in all variables following Max-ECC were smaller (P < 0.05) for 2-day, 1- and 2-week groups than control group, without significant differences between 2-day and 1-week groups. The 2-week group showed greater (P < 0.05) changes in all variables compared with 2-day and 1-week groups. Changes in the variables were similar between 3-week and control groups, except for muscle soreness showing smaller (P < 0.05) changes for 3-week group. These results suggest that non-damaging eccentric exercise confers a protective effect against Max-Ecc, but the effect is attenuated between 1 and 2 weeks.
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Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.