Evidence map›Paper›PMID 21609465›Full record

ReviewJournal of hematology & oncology2011

Endothelial progenitor cell biology in disease and tissue regeneration.

Andrea L George, Pradeep Bangalore-Prakash, Shilpi Rajoria, Robert Suriano, Arulkumaran Shanmugam, Abraham Mittelman, Raj K Tiwari

Open access · goldAbstract readReview
In one paragraph

Review in Journal of hematology & oncology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 1 pooled it
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 1 synthesis or guideline pooled it, 159 citations in OpenAlex.

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5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Andrea L GeorgeDepartment of Microbiology and Immunology, New York Medical College, Valhalla, New York, USA.
Pradeep Bangalore-Prakash
Shilpi Rajoria
Robert Suriano
Arulkumaran Shanmugam
Abraham Mittelman
Raj K Tiwari
New York Medical College · US

Funding

Intervention models for thyroid proliferative disease using a bioactive food compR01CA131946 · NCI · NEW YORK MEDICAL COLLEGE · PI TIWARI, RAJ K · 2009 to 2013
$1.6M
NCI NIH HHS 1R01CA131946
6 · The paper itself

Abstract

Endothelial progenitor cells are increasingly being studied in various diseases ranging from ischemia, diabetic retinopathy, and in cancer. The discovery that these cells can be mobilized from their bone marrow niche to sites of inflammation and tumor to induce neovasculogenesis has afforded a novel opportunity to understand the tissue microenvironment and specific cell-cell interactive pathways. This review provides a comprehensive up-to-date understanding of the physiological function and therapeutic utility of these cells. The emphasis is on the systemic factors that modulate their differentiation/mobilization and survival and presents the challenges of its potential therapeutic clinical utility as a diagnostic and prognostic reagent.

Indexed as

AnimalsEndothelial CellsHumansMiceNeovascularization, PhysiologicRegenerationStem Cells

Identifiers

PMID21609465
PMCPMC3123653
OpenAlexW2101018118

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.