ArticleParasitology research2012
Detection of Cryptosporidium parvum and Cryptosporidium hominis in human patients in Cairo, Egypt.
Article in Parasitology research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.
- Human cryptosporidiosis in Iran: a systematic review and meta-analysis.Parasitology research · 2017Pooled it
- Molecular prevalence ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2021Article
- Performance of formalin ethyl acetate, percoll sedimentation and ELISA for the detection ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2021Article
- Molecular Epidemiology of Human Cryptosporidiosis in Low- and Middle-Income Countries.Clinical microbiology reviews · 2021Review
- Article
- Molecular characterization of Cryptosporidium spp. and Giardia duodenalis in children in Egypt.Parasites & vectors · 2018Article
- A Comprehensive Review of Common Bacterial, Parasitic and Viral Zoonoses at the Human-Animal Interface in Egypt.Pathogens (Basel, Switzerland) · 2017Review
- Cryptosporidium and Giardia in Africa: current and future challenges.Parasites & vectors · 2017Review
- Low sensitivity of the ImmunocardSTATJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2016Article
- Cryptosporidium and cryptosporidiosis: the African perspective.Environmental science and pollution research international · 2016Review
- Epidemiology and public health significance of Cryptosporidium isolated from cattle, buffaloes, and humans in Egypt.Parasitology research · 2016Article
- Molecular seasonal, age and gender distributions of Cryptosporidium in diarrhoeic Egyptians: distinct endemicity.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2015Article
- Frequencies and spatial distributions of Cryptosporidium in livestock animals and children in the Ismailia province of Egypt.Epidemiology and infection · 2015Article
- Molecular characterization of Cryptosporidium spp. among children in rural Ghana.PLoS neglected tropical diseases · 2015Article
- Use of multiplex real-time PCR for detection of common diarrhea causing protozoan parasites in Egypt.Parasitology research · 2013Article
- Cryptosporidiosis: comparison of three diagnostic methods and effects of storage temperature on detectability of cryptosporidia in cattle faeces.Parasitology research · 2012Article
- The importance of subtype analysis of Cryptosporidium spp. in epidemiological investigations of human cryptosporidiosis in Iran and other Mideast countries.Gastroenterology and hepatology from bed to bench · 2012Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cryptosporidium is a significant cause of diarrheal disease in developing and industrialized nations. Cryptosporidium hominis and Cryptosporidium parvum are the main agents of cryptosporidiosis in humans. In Egypt, very little is known about genetic structure of Cryptosporidium spp. Therefore, this study was designed to examine samples from sporadic cases of cryptosporidiosis in Egyptians in order to identify the species involved in infection as well as the transmission dynamics and distribution of the parasite in the Great Cairo area. A total of 391 human faecal samples were collected, between May 2008 and March 2009, from ten public hospitals in Great Cairo. Initial screening by immunochromatographic detection kit "the Stick Crypto-Giardia; Operon" showed 23 possible positive cases. Twenty of them were confirmed by microscopic examination. PCR was performed by amplification of the oocyst wall protein (COWP) gene where 18 out of 23 samples were positive, one not detected by microscopy. Cryptosporidium genotyping was performed by RFLP analysis of PCR products of the diagnosis PCR. Only 15 samples rendered a digestion pattern. The genotyping distribution was nine cases showing C. hominis genotype, three showing C. parvum genotype and three showing mixed infection by C. hominis and C. parvum. The data showed an elevated prevalence of C. hominis (80.0%), the most anthroponotic species, suggesting a human-human transmission. Furthermore, the presence of up to 40% of samples infected with C. parvum shows that further investigations are required to determine the subgenotypes of C. parvum to clarify the mode of transmission in order to improve the control measures.
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