ArticleJapanese journal of ophthalmology2011
Conjunctival swabs and corneoscleral rim cultures from corneal transplantation donors as possible early indicators for posttransplant endopthalmitis.
Article in Japanese journal of ophthalmology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 14 citations in OpenAlex.
- Effectiveness of 1.25 % povidone-iodine combined with topical levofloxacin against conjunctival flora in intravitreal injection.Japanese journal of ophthalmology · 2012Trial
- Microbial contamination of donor corneoscleral rims and storage medium in keratoplasty.Japanese journal of ophthalmology · 2026Article
- The Prevalence of Positive Donor Corneoscleral Rim Culture and its Association with Ocular Infection After Transplantation.Beyoglu eye journal · 2023Article
- Microorganism detection and contamination rate of donor eyes in Japan.Japanese journal of ophthalmology · 2020Article
- Donor-Dependent Factors Influencing Contamination Rates of Conjunctival Swabs of Human Donor Eyes.Annals of transplantation · 2019Article
- Factors influencing the contamination rates of the conjunctival swabs and organ culture media of human donor eyes.Medicine · 2018Observational
- Pre-banking microbial contamination of donor conjunctiva and storage medium for penetrating keratoplasty.Japanese journal of ophthalmology · 2017Article
- The value of corneoscleral rim cultures in keratoplasty: a systematic review and cost-effectiveness analysis.ClinicoEconomics and outcomes research : CEOR · 2017Review
- Bacterial flora of conjunctiva after death.International journal of ophthalmology · 2013Article
- Prevalence of microbial contamination in donor corneas.Taiwan journal of ophthalmologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo determine by microbiological examinations the rate of conjunctiva and corneoscleral rim contamination of cadaver donor tissues.
methodsA prospective review of culture results for 98 cadaver donor conjunctival swabs [mean age 76.4 ± 12.9 years (±SD)]. Transplant patients were evaluated both before and after disinfection with gentamicin. Individual parameters evaluated included detection rates of bacteria, variety of detected bacteria, time interval from donor death to tissue harvest and age of donors.
resultsBefore disinfection, 60 out of 98 conjunctival swabs exhibited microbial growth, while only 36 out of 98 exhibited growth after disinfection (p = 0.0006). Longer intervals between death and tissue harvest were associated with higher positive microbial growth rates. Prior to disinfection, culture-positive donors (74.1 ± 13.6 years) were significantly younger than culture-negative donors (79.8 ± 10.8 years) (p = 0.024). Positive donor rim cultures were noted in 2 out of the 22 corneal transplantations. Microorganisms isolated from the corneal grafts matched those found in the conjunctiva.
conclusionsIt is recommended that the corneoscleral buttons be removed as soon as possible. Cultures of conjunctival swabs collected from donors after disinfection may be useful in determining treatment for postoperative infections occurring after corneal transplantation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.