ArticleWorld journal of urology2011
Color Doppler ultrasound imaging in varicoceles: is the venous diameter sufficient for predicting clinical and subclinical varicocele?
Article in World journal of urology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 3 syntheses or guidelines pooled it, 88 citations in OpenAlex.
- Ultrasound evaluation of varicoceles: systematic literature review and rationale of the ESUR-SPIWG Guidelines and Recommendations.Journal of ultrasound · 2020Pooled it
- Ultrasound evaluation of varicoceles: guidelines and recommendations of the European Society of Urogenital Radiology Scrotal and Penile Imaging Working Group (ESUR-SPIWG) for detection, classification, and grading.European radiology · 2020Guideline
- The association between body mass index and varicocele: A meta-analysis.International braz j urol : official journal of the Brazilian Society of UrologyPooled it
- Multiple determinations of sperm DNA fragmentation show that varicocelectomy is not indicated for infertile patients with subclinical varicocele.BioMed research international · 2014Trial
- Is Varicocele Truly Unilateral? Contralateral Involvement and Bilateral Testicular Effects in Male Infertility: A Narrative Review.Journal of personalized medicine · 2026Review
- Ultrasound maximum vein diameter contextualizes testicular asymmetry in adolescent varicocele.International urology and nephrology · 2026Article
- A sound approach to stay on the ball-a review of scrotal pathologies on ultrasound imaging.The British journal of radiology · 2026Review
- Global Andrology Forum (GAF) Clinical Guidelines on the Management of Infertile Men with Varicocele.The world journal of men's health · 2026Article
- Testicular microenvironment disruption in varicocele: mechanisms and implications for spermatogenesis.Frontiers in endocrinology · 2026Review
- Association between Hidradenitis Suppurativa and Abnormalities in Semen Parameters and Sexual Function: A Pilot Study.Acta dermato-venereologica · 2023Article
- Color Doppler ultrasound imaging in varicoceles: Is the difference in venous diameter encountered during Valsalva predictive of palpable varicocele grade?Asian journal of urology · 2023Article
- Consensus and Diversity in the Management of Varicocele for Male Infertility: Results of a Global Practice Survey and Comparison with Guidelines and Recommendations.The world journal of men's health · 2023Article
- The usefulness of elastography in the evaluation and management of adult men with varicocele: A systematic review.Arab journal of urology · 2021Article
- The use of scrotal ultrasound in the evaluation of varicoceles: A survey study of reproductive specialists.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2020Article
- [Varicocele in children and adolescents-conservative vs. surgical treatment?]Der Urologe. Ausg. A · 2020Review
- High prevalence of urogenital infection/inflammation in patients with azoospermia does not impede surgical sperm retrieval.Andrologia · 2019Article
- Clinical grading and color Doppler ultrasonography-based grading of varicocele: how compatible are the two grading systems?World journal of urology · 2019Article
- Correlation between Testicular Hemodynamic and Semen Quality Indices in Clinical Varicocele Patients in Pakistan.BioMed research international · 2019Article
- Sonography in male infertility: a look beyond the obvious.Journal of ultrasound · 2018Review
- Determination of spermatic vein reflux after varicocele repair helps to define the efficacy of treatment in improving sperm parameters of subfertile men.Journal of endocrinological investigation · 2017Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeInvestigating the diagnostic value of color Doppler ultrasound for defining the varicocele grade according to WHO criteria.
methodsA total of 217 men (129 with clinical varicocele and 88 without clinical varicocele) were investigated by physical examination and color Doppler ultrasound and categorized according to WHO varicocele criteria (0, subclinical, I, II, and III). Diameter and reflux of the largest vein in the pampiniform plexus were measured bilaterally with the patient in the supine position in rest and during the Valsalva maneuver. To assess the possibility of differentiating varicocele grade by venous diameter, optimal cut-point values were determined by receiver-operator characteristic (ROC) analysis.
resultsWith increased varicocele grade, a larger vein diameter was more significant in rest and during Valsalva (in all cases P < 0.05), except between grade I and grade II. Retrograde peak flow velocities were similar in every group (in all cases P > 0.1). Only grade III varicoceles demonstrated significantly increased peak flow values compared with all other grades (P < 0.001). There were no side-related differences when comparing identical varicocele grades (in all cases P > 0.1). Venous diameters above 2.45 mm in rest (sensitivity 84%, specificity 81%) or 2.95 mm during Valsalva (sensitivity 84%, specificity 84%) predicted the presence of a clinical varicocele.
conclusionsOur findings support the hypothesis that clinical varicoceles can be predicted with high accuracy based only on the diameter of testicular veins using cut-point values of >2.45 mm in rest or >2.95 mm during Valsalva maneuver in the supine position.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.