Evidence map›Paper›PMID 21607143›Full record

ArticleWorld journal of gastrointestinal pathophysiology2010

Biogenic amines serotonin and dopamine regulate cholangiocyte hyperplastic and neoplastic growth.

Gabriel A Frampton, Huang Li, Jonathan Ramirez, Akimuddin Mohamad, Sharon Demorrow

Abstract read
In one paragraph

Article in World journal of gastrointestinal pathophysiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gabriel A FramptonGabriel A Frampton, Huang Li, Akimuddin Mohamad, Department of Medicine, Texas A&M Health Science Center, College of Medicine, Temple, TX 76504, United States.
Huang Li
Jonathan Ramirez
Akimuddin Mohamad
Sharon Demorrow

Funding

Endocannabinoid Regulation of Cholangiocarcinoma Cell GrowthK01DK078532 · NIDDK · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI DEMORROW, SHARON · 2007 to 2011
$697k
NIDDK NIH HHS K01 DK078532
6 · The paper itself

Abstract

Biogenic amines, such as serotonin and dopamine, regulate a multitude of cellular responses. A great deal of effort has been invested into understanding the effects of these molecules and their corresponding receptor systems on cholangiocyte and cholangiocarcinoma secretion, apoptosis and growth. This review summarizes the results of these efforts and highlights the importance of these regulatory molecules on the physiology and pathophysiology of cholangiocytes. Specifically we have focused on the recent findings into the effects of serotonin and dopamine on cholangiocyte hyperplasia and neoplastic growth.

Indexed as

CholangiocarcinomaDuctal secretionMonoamine oxidase ATryptophan hydroxylase 1Tyrosine hydroxylase

Identifiers

PMID21607143
PMCPMC3097942

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.