Evidence map›Paper›PMID 21607141›Full record

ArticleWorld journal of gastrointestinal pathophysiology2010

Histamine regulation of hyperplastic and neoplastic cell growth in cholangiocytes.

Paolo Onori, Eugenio Gaudio, Antonio Franchitto, Gianfranco Alpini, Heather Francis

Open access · greenAbstract read
In one paragraph

Article in World journal of gastrointestinal pathophysiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Histamine receptors and cancer pharmacology: an update.British journal of pharmacology · 2020
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Paolo OnoriPaolo Onori, Experimental Medicine, University of L'Aquila, L'Aquila 67100, Italy.
Eugenio Gaudio
Antonio Franchitto
Gianfranco Alpini
Heather Francis
University of L'Aquila · IT

Funding

GROWTH REGULATION OF THE INTRAHEPATIC BILIARY TREER01DK054811 · NIDDK · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI ALPINI, GIANFRANCO D, GLASER, SHANNON STROUD · 2000 to 2021
$3.8M
Role of Sensory Neuropeptides in the Regulation of Biliary FunctionR01DK076898 · NIDDK · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI ALPINI, GIANFRANCO D, GLASER, SHANNON STROUD · 2008 to 2016
$1.8M
TOWARD THE OPTIMAL TIMING OF INITIATION OF DIALYSISR01DK058411 · NIDDK · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI CHERTOW, GLENN MATTHEW · 2001 to 2003
$1.8M
NIDDK NIH HHS R01 DK054811NIDDK NIH HHS R01 DK058411NIDDK NIH HHS R01 DK076898
6 · The paper itself

Abstract

Histamine has long been known to be involved in inflammatory events. The discovery of antihistamines dates back to the first half of the 20(th) century when a Swiss-Italian pharmacologist, Daniel Bovet began his work. In 1957 he was awarded a Nobel Prize for his production of antihistamines for allergy relief. Since that time, histamine has been found to play a role in other events besides allergic reaction. Possibly unbelievable to Bovet and his peers, histamine has now been marked as playing a role in liver pathologies including hepatobiliary diseases.

Indexed as

CholangiocarcinomaCholangiocytesCholestasisHistamineReceptors

Identifiers

PMID21607141
PMCPMC3097946
OpenAlexW1984865466

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.