ArticleThe Journal of infectious diseases2011
Circulating influenza virus, climatic factors, and acute myocardial infarction: a time series study in England and Wales and Hong Kong.
Article in The Journal of infectious diseases, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 4 of them syntheses that pooled it.
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Who cites it
67 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Influenza Vaccination for Cardiovascular Prevention: Further Insights from the IAMI Trial and an Updated Meta-analysis.Current cardiology reports · 2022Pooled it
- Moving the Needle on Atherosclerotic Cardiovascular Disease and Heart Failure with Influenza Vaccination.Current atherosclerosis reports · 2021Pooled it
- Influenza, influenza-like symptoms and their association with cardiovascular risks: a systematic review and meta-analysis of observational studies.International journal of clinical practice · 2015Pooled it
- Influenza vaccines for preventing cardiovascular disease.The Cochrane database of systematic reviews · 2015Pooled it
- High-Dose Quadrivalent Influenza Vaccine for Prevention of Cardiovascular and Respiratory Hospitalizations in Older Adults.Influenza and other respiratory viruses · 2024Trial
- Alternative approaches to phase III clinical trials for vaccine efficacy and licensure: the role of real-world evidence - a meeting report.Biologicals : journal of the International Association of Biological Standardization · 2026Article
- Spatio-temporal patterns and associated factors of influenza-like illness outbreaks in Chinese mainland: a Bayesian modeling study.BMC public health · 2025Article
- Influenza Activity and Preterm Birth in the Atlanta Metropolitan Area: A Time-Series Analysis from 2010 to 2017.Epidemiology (Cambridge, Mass.) · 2025Article
- Prevalence of influenza and other acute respiratory illnesses in patients with acute myocardial infarction in Bangladesh: A cross-sectional study.Health science reports · 2024Article
- Exposome in ischaemic heart disease: beyond traditional risk factors.European heart journal · 2024Review
- Article
- Association of recent respiratory illness and influenza with acute myocardial infarction among the Bangladeshi population: A case-control study.Epidemiology and infection · 2023Article
- [Influence of meteorological factors on the severity of COVID-19 in Spain: Observational ecological study].Medicina clinica · 2023Article
- Influence of meteorological factors on the severity of COVID-19 in Spain: Observational ecological study.Medicina clinica (English ed.) · 2023Article
- Sex and molecular differences in cardiovascular parameters at peak influenza disease in mice.Physiological genomics · 2023Article
- Seasonal dynamics of myocardial infarctions in regions with different types of a climate: a meta-analysis.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2022Review
- Clinical and economic burden of physician-diagnosed influenza in adults during the 2017/2018 epidemic season in Spain.BMC public health · 2022Article
- All-cause versus cause-specific excess deaths for estimating influenza-associated mortality in Denmark, Spain, and the United States.Influenza and other respiratory viruses · 2022Article
- Patients with Obesity and a History of Metformin Treatment Have Lower Influenza Mortality: A Retrospective Cohort Study.Pathogens (Basel, Switzerland) · 2022Article
- Modelling the influenza disease burden in people aged 50-64 and ≥65 years in Australia.Influenza and other respiratory viruses · 2022Article
7 more citing papers are in PubMed but not listed here.
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Authors and funding
10 authors.
Funding
Abstract
backgroundPrevious studies identifying associations between influenza and acute cardiac events may have been confounded by climatic factors. Differing seasonal patterns of influenza activity in Hong Kong and England and Wales provide a natural experiment to examine associations with myocardial infarction (MI) independent of cold weather effects.
methodsWeekly clinical and laboratory influenza surveillance data, environmental temperature and humidity data, and counts of MI-associated hospitalizations and deaths were obtained for England and Wales and for Hong Kong for the period 1998-2008. We used Poisson regression models that included environmental and seasonal variables to investigate the relationship between influenza and MI.
resultsThere were ≥1.2 million MI-associated hospitalizations and 410,204 MI-associated deaths in England and Wales, with a marked peak in the winter season. In Hong Kong, the incidence of MI, on the basis of 65,108 hospitalizations and 18,780 deaths, had a large winter and smaller summer peak, mirroring patterns of influenza activity. There was strong evidence for a link between influenza and MI both in England and Wales, where 3.1%-3.4% of MI-associated deaths (P < .001) and 0.7%-1.2% of MI-associated hospitalizations (P < .001) were attributable to influenza, and in Hong Kong, where the corresponding figures were 3.9%-5.6% (P = .018) and 3.0%-3.3% (P = .002).
conclusionsInfluenza was associated with an increase in MI-associated deaths and hospitalizations in 2 contrasting settings.
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