Evidence map›Paper›PMID 21606181›Full record

ReviewCardiovascular research2011

Epigenetic factors and cardiac development.

Jan Hendrick van Weerd, Kazuko Koshiba-Takeuchi, Chulan Kwon, Jun K Takeuchi

Abstract readReview
In one paragraph

Review in Cardiovascular research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Investigation of the Role ofDiagnostics (Basel, Switzerland) · 2023
    Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Role of Nkx2.5 in HCell stress & chaperones · 2019
    Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jan Hendrick van WeerdCardiovascular Regeneration, Institute of Molecular and Cellular Biosciences, University of Tokyo, Tokyo, Japan.
Kazuko Koshiba-Takeuchi
Chulan Kwon
Jun K Takeuchi

Funding

Isl1 and Wntbeta-catenin regulation of cardiac progenitor cellsR00HL092234 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI KWON, CHULAN · 2011 to 2013
$730k
Isl1 and Wntbeta-catenin regulation of cardiac progenitor cellsK99HL092234 · NHLBI · J. DAVID GLADSTONE INSTITUTES · PI KWON, CHULAN · 2009 to 2010
$206k
NHLBI NIH HHS K99 HL092234NHLBI NIH HHS R00 HL092234NHLBI NIH HHS R00HL092234
6 · The paper itself

Abstract

Congenital heart malformations remain the leading cause of death related to birth defects. Recent advances in developmental and regenerative cardiology have shed light on a mechanistic understanding of heart development that is controlled by a transcriptional network of genetic and epigenetic factors. This article reviews the roles of chromatin remodelling factors important for cardiac development with the current knowledge of cardiac morphogenesis, regeneration, and direct cardiac differentiation. In the last 5 years, critical roles of epigenetic factors have been revealed in the cardiac research field.

Indexed as

Epigenesis, GeneticGene Expression Regulation, DevelopmentalAnimalsCell DifferentiationCell LineageCell ProliferationChromatin Assembly and DisassemblyHeartHeart Defects, CongenitalHumansMorphogenesisMuscle DevelopmentRegenerationRegenerative MedicineSignal TransductionTranscription FactorsTranscription Factors

Identifiers

PMID21606181
PMCPMC3125076

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.