Evidence map›Paper›PMID 21606133›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA

ImageMiner: a software system for comparative analysis of tissue microarrays using content-based image retrieval, high-performance computing, and grid technology.

David J Foran, Lin Yang, Wenjin Chen, Jun Hu, Lauri A Goodell, Michael Reiss, Fusheng Wang, Tahsin Kurc, Tony Pan, Ashish Sharma and 1 more

Abstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. AI in Medical Imaging Informatics: Current Challenges and Future Directions.IEEE journal of biomedical and health informatics · 2020
    Article
  6. PRISM: A Platform for Imaging in Precision Medicine.JCO clinical cancer informatics · 2020
    Article
  7. Article
  8. Distributed and parallel databases · 2019
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Towards Generation, Management, and Exploration of Combined Radiomics and Pathomics Datasets for Cancer Research.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2017
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

David J ForanCenter for Biomedical Imaging & Informatics, UMDNJ-Robert Wood Johnson Medical School, New Brunswick, New Jersey 08901, USA.
Lin Yang
Wenjin Chen
Jun Hu
Lauri A Goodell
Michael Reiss
Fusheng Wang
Tahsin Kurc
Tony Pan
Ashish Sharma
Joel H Saltz

Funding

TRANSCRIPTIONAL PROFILINGP30CA072720 · NCI · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI Shridar Ganesan · 1997 to 2026
$94.5M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025008 · NCRR · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2007 to 2011
$29.0M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
The CardioVascular Research GridR24HL085343 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI WINSLOW, RAIMOND LESTER · 2007 to 2015
$19.4M
Predicting Drug Resistance in Cancer Genomes by DMA Methylation ProfilingU54CA113001 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI HUANG, TIM H.-M. · 2004 to 2014
$16.1M
Image Mining for Comparative Analysis of Expression Patterns in Tissue MicroarrayR01LM009239 · NLM · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI FORAN, DAVID J, SALTZ, JOEL H. · 2007 to 2016
$4.5M
Tools to Analyze Morphology and Spatially Mapped Molecular DataU24CA180924 · NCI · STATE UNIVERSITY NEW YORK STONY BROOK · PI SALTZ, JOEL H. · 2014 to 2019
$3.6M
Center for Grid-Enabled Medical Image AnalysisP20EB000591 · NIBIB · OHIO STATE UNIVERSITY · PI SALTZ, JOEL H · 2003 to 2005
$2.1M
Informatics for Integrative Brain Tumor Whole Slide AnalysisR01LM011119 · NLM · STATE UNIVERSITY NEW YORK STONY BROOK · PI FORAN, DAVID J, SALTZ, JOEL H. · 2011 to 2014
$1.8M
Collaborative Systems for Analyzing Tissue MicroarraysR01CA156386 · NCI · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI FORAN, DAVID J · 2010 to 2014
$1.7M
NCATS NIH HHS UL1 TR000454NCI NIH HHS 9R01CA156386-05A1NCI NIH HHS N01 CO012400NCI NIH HHS N01-CO-12400NCI NIH HHS P30 CA072720NCI NIH HHS R01 CA156386NCI NIH HHS U24 CA180924NCI NIH HHS U54 CA113001NCRR NIH HHS UL1 RR025008NCRR NIH HHS UL1RR025008NHLBI NIH HHS R24 HL085343NIBIB NIH HHS P20 EB000591NLM NIH HHS 3R01LM009239-03S2NLM NIH HHS 5R01LM009239-04NLM NIH HHS R01 LM009239NLM NIH HHS R01 LM011119PHS HHS 29XS154PHS HHS 79077CBS10PHS HHS 85983CBS43PHS HHS 94995NBS23
6 · The paper itself

Abstract

OBJECTIVE AND

designThe design and implementation of ImageMiner, a software platform for performing comparative analysis of expression patterns in imaged microscopy specimens such as tissue microarrays (TMAs), is described. ImageMiner is a federated system of services that provides a reliable set of analytical and data management capabilities for investigative research applications in pathology. It provides a library of image processing methods, including automated registration, segmentation, feature extraction, and classification, all of which have been tailored, in these studies, to support TMA analysis. The system is designed to leverage high-performance computing machines so that investigators can rapidly analyze large ensembles of imaged TMA specimens. To support deployment in collaborative, multi-institutional projects, ImageMiner features grid-enabled, service-based components so that multiple instances of ImageMiner can be accessed remotely and federated.

resultsThe experimental evaluation shows that: (1) ImageMiner is able to support reliable detection and feature extraction of tumor regions within imaged tissues; (2) images and analysis results managed in ImageMiner can be searched for and retrieved on the basis of image-based features, classification information, and any correlated clinical data, including any metadata that have been generated to describe the specified tissue and TMA; and (3) the system is able to reduce computation time of analyses by exploiting computing clusters, which facilitates analysis of larger sets of tissue samples.

Indexed as

Database Management SystemsImage Processing, Computer-AssistedData MiningHumansInformation DisseminationSoftware DesignTissue Array AnalysisUnited States

Identifiers

PMID21606133
PMCPMC3128405

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.