ArticleMolecular and cellular biology1990
Multimeric arrays of the yeast retrotransposon Ty.
Article in Molecular and cellular biology, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed.
- Retrotransposon targeting to RNA polymerase III-transcribed genes.Mobile DNA · 2018Review
- Review
- Rrm3 protects the Saccharomyces cerevisiae genome from instability at nascent sites of retrotransposition.Genetics · 2009Article
- The take and give between retrotransposable elements and their hosts.Annual review of genetics · 2008Review
- Retrosequence formation restructures the yeast genome.Genes & development · 2007Article
- Ty1 copy number dynamics in Saccharomyces.Genetics · 2005Article
- Article
- The Sgs1 helicase of Saccharomyces cerevisiae inhibits retrotransposition of Ty1 multimeric arrays.Molecular and cellular biology · 2001Article
- Fission yeast retrotransposon Tf1 integration is targeted to 5' ends of open reading frames.Nucleic acids research · 2000Article
- The Saccharomyces cerevisiae DNA recombination and repair functions of the RAD52 epistasis group inhibit Ty1 transposition.Genetics · 2000Article
- cDNA of the yeast retrotransposon Ty5 preferentially recombines with substrates in silent chromatin.Molecular and cellular biology · 1999Article
- The pheromone response pathway activates transcription of Ty5 retrotransposons located within silent chromatin of Saccharomyces cerevisiae.The EMBO journal · 1997Article
- High frequency cDNA recombination of the saccharomyces retrotransposon Ty5: The LTR mediates formation of tandem elements.Genetics · 1997Article
- Increased length of long terminal repeats inhibits Ty1 transposition and leads to the formation of tandem multimers.Genetics · 1997Article
- Efficient homologous recombination of Ty1 element cDNA when integration is blocked.Molecular and cellular biology · 1994Article
- An in vivo assay for the reverse transcriptase of human retrotransposon L1 in Saccharomyces cerevisiae.Molecular and cellular biology · 1994Article
- A ubiquitin-conjugating enzyme, RAD6, affects the distribution of Ty1 retrotransposon integration positions.Genetics · 1993Article
- Rearrangements occurring adjacent to a single Ty1 yeast retrotransposon in the presence and absence of full-length Ty1 transcription.Genetics · 1992Article
- The population biology and evolutionary significance of Ty elements in Saccharomyces cerevisiae.Genetica · 1992Review
- Proteolytic processing of pol-TYB proteins from the yeast retrotransposon Ty1.Journal of virology · 1991Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
We have identified a novel integrated form of the yeast retrotransposon Ty consisting of multiple elements joined into large arrays. These arrays were first identified among Ty-induced alpha-pheromone-resistant mutants of MATa cells of Saccharomyces cerevisiae which contain Ty insertions at HML alpha that result in the expression of that normally silent cassette. These insertions are multimeric arrays of both the induced genetically marked Ty element and unmarked Ty elements. Structural analysis of the mutations indicated that the arrays include tandem direct repeats of Ty elements separated by only a single long terminal repeat. The Ty-HML junction fragments of one mutant were cloned and shown to contain a 5-base-pair duplication of the target sequence that is characteristic of a Ty transpositional insertion. In addition, the arrays include rearranged Ty elements that do not have normal long terminal repeat junctions. We have also identified multimeric Ty insertions at other chromosomal sites and as insertions that allow expression of a promoterless his3 gene on a plasmid. The results suggest that Ty transposition includes an intermediate that can undergo recombination to produce multimers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.