Evidence map›Paper›PMID 21605683›Full record

ArticleJournal of structural biology2011

xtalPiMS: a PiMS-based web application for the management and monitoring of crystallization trials.

Ed Daniel, Bill Lin, Jonathan M Diprose, Susanne L Griffiths, Chris Morris, Ian M Berry, Raymond J Owens, Richard Blake, Keith S Wilson, David I Stuart and 1 more

Abstract read
In one paragraph

Article in Journal of structural biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. In situ macromolecular crystallography using microbeams.Acta crystallographica. Section D, Biological crystallography · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ed DanielCSED, STFC Daresbury Laboratory, Warrington WA44AD, UK.
Bill Lin
Jonathan M Diprose
Susanne L Griffiths
Chris Morris
Ian M Berry
Raymond J Owens
Richard Blake
Keith S Wilson
David I Stuart
Robert M Esnouf

Funding

Biotechnology and Biological Sciences Research Council BBC5121101Biotechnology and Biological Sciences Research Council BBC5121291Biotechnology and Biological Sciences Research Council BBC5121371Biotechnology and Biological Sciences Research Council BBC5121451Medical Research Council G0701506Medical Research Council G1000099Medical Research Council G1100525Medical Research Council G19/3Wellcome Trust 075491/Z/04Wellcome Trust 090532
6 · The paper itself

Abstract

A major advance in protein structure determination has been the advent of nanolitre-scale crystallization and (in a high-throughput environment) the development of robotic systems for storing and imaging crystallization trials. Most of these trials are carried out in 96-well (or higher density) plates and managing them is a significant information management challenge. We describe xtalPiMS, a web-based application for the management and monitoring of crystallization trials. xtalPiMS has a user-interface layer based on the standards of the Protein Information Management System (PiMS) and a database layer which links the crystallization trial images to the meta-data associated with a particular crystallization trial. The user interface has been optimized for the efficient monitoring of high-throughput environments with three different automated imagers and work to support a fourth imager is in progress, but it can even be of use without robotics. The database can either be a PiMS database or a legacy database for which a suitable mapping layer has been developed.

Indexed as

Database Management SystemsCrystallography, X-RayDatabases, ProteinInformation ManagementOnline SystemsProteinsUser-Computer InterfaceProteins

Identifiers

PMID21605683
PMCPMC3477317

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.