Evidence map›Paper›PMID 21605435›Full record

ArticleBMC family practice2011

Up-beat UK: a programme of research into the relationship between coronary heart disease and depression in primary care patients.

André Tylee, Mark Ashworth, Elizabeth Barley, June Brown, John Chambers, Anne Farmer, Zoe Fortune, Mark Haddad, Rebecca Lawton, Anthony Mann and 9 more

Open access · goldAbstract read
In one paragraph

Article in BMC family practice, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Collaborative care for depression and anxiety problems.The Cochrane database of systematic reviews · 2012
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  7. Using a patient-generated mental-health measure 'PSYCHLOPS' to explore problems in patients with coronary heart disease.The British journal of general practice : the journal of the Royal College of General Practitioners · 2014
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 2 countries.

André TyleeHealth Services and Population Research Dept., Institute of Psychiatry, King's College London, UK. a.tylee@iop.kcl.ac.uk
Mark Ashworth
Elizabeth Barley
June Brown
John Chambers
Anne Farmer
Zoe Fortune
Mark Haddad
Rebecca Lawton
Anthony Mann
Anita Mehay
Paul McCrone
Joanna Murray
Morven Leese
Carmine M Pariante
Diana Rose
Gill Rowlands
Alison Smith
Paul Walters
King's College London · GBLondon South Bank University · GBPsychiatry Research Trust · GBSt Thomas' Hospital · GB

Funding

Department of Health RP-PG-0606-1048Medical Research Council G108/603
6 · The paper itself

Abstract

backgroundCoronary heart disease and depression are both common health problems and by 2020 will be the two leading causes of disability worldwide. Depression has been found to be more common in patients with coronary heart disease but the nature of this relationship is uncertain. In the United Kingdom general practitioners are now being remunerated for case-finding for depression in patients with coronary heart disease, however it is unclear how general practitioners should manage these patients. We aim to explore the relationship between coronary heart disease and depression in a primary care population and to develop an intervention for patients with coronary heart disease and depression. METHODS/

designThis programme of research will consist of 4 inter-related studies. A 4 year prospective cohort study of primary care patients with coronary heart disease will be conducted to explore the relationship between coronary heart disease and depression. Within this, a nested case-control biological study will investigate genetic and blood-biomarkers as predictors of depression in this sample. Two qualitative studies, one of patients' perspectives of treatments for coronary heart disease and co-morbid depression and one of primary care professionals' views on the management of patients with coronary heart disease and depression will inform the development of an intervention for this patient group. A feasibility study for a randomised controlled trial will then be conducted. DISCUSSION: This study will provide information on the relationship between coronary heart disease and depression that will allow health services to determine the efficiency of case-finding for depression in this patient group. The results of the cohort study will also provide information on risk factors for depression. The study will provide evidence on the efficacy and feasibility of a joint patient and professional led intervention and data necessary to plan a definitive randomised controlled trial of the intervention.

Indexed as

Primary Health CareCase ManagementCohort StudiesCoronary DiseaseDepressionFeasibility StudiesHumansPatientsPerceptionPhysicians, Primary CareQualitative ResearchResearch DesignUnited Kingdom

Identifiers

PMID21605435
PMCPMC3120657
OpenAlexW2113158916

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.