ArticlePharmacoEconomics2011
Cost-of-illness studies: a guide to critical evaluation.
Article in PharmacoEconomics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 211 papers, 51 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
211 citing papers in PubMed, 51 syntheses or guidelines pooled it.
- Adverse Drug Reaction Costs and Study Quality in Africa: A Systematic Review of Cost-of-Illness Studies.PharmacoEconomics - open · 2026Pooled it
- The economic burden of Type 2 Diabetes by social determinants of health: A systematic review.PloS one · 2026Pooled it
- The Economic Burden of Inflammatory Arthritis: A Systematic Review.PharmacoEconomics · 2025Pooled it
- An Updated Systematic Literature Review of the Economic Costs of Loneliness and Social Isolation and the Cost Effectiveness of Interventions.PharmacoEconomics · 2025Pooled it
- What are the costs associated with nausea and vomiting in pregnancy and hyperemesis gravidarum? A systematic review.BMC pregnancy and childbirth · 2025Pooled it
- Economic Burden of Acute Myeloid Leukemia in European Union: Results from a Systematic Review of Literature.PharmacoEconomics - open · 2025Pooled it
- Barriers to cancer screening uptake and approaches to overcome them: a systematic literature review.Frontiers in oncology · 2025Pooled it
- Clinical, humanistic and economic burden associated with recurrence among patients with early-stage cancers: a systematic literature review.Frontiers in oncology · 2025Pooled it
- Assessing the clinical, humanistic, and economic impact of early cancer diagnosis: a systematic literature review.Frontiers in oncology · 2025Pooled it
- Global and Regional Economic Burden of Eating Disorders: A Systematic Review and Critique of Methods.The International journal of eating disorders · 2025Pooled it
- The epidemiologic and economic burden of dengue in Singapore: A systematic review.PLoS neglected tropical diseases · 2024Pooled it
- Financial hardship among patients suffering from neglected tropical diseases: A systematic review and meta-analysis of global literature.PLoS neglected tropical diseases · 2024Pooled it
- The global economic burden of COVID-19 disease: a comprehensive systematic review and meta-analysis.Systematic reviews · 2024Pooled it
- The economic burden of Chagas disease: A systematic review.PLoS neglected tropical diseases · 2023Pooled it
- A consensus-based checklist for the critical appraisal of cost-of-illness (COI) studies.International journal of technology assessment in health care · 2023Guideline
- The economic burden of treating uncomplicated hypertension in Sub-Saharan Africa: a systematic literature review.BMC public health · 2022Pooled it
- The economic burden of dementia in low- and middle-income countries (LMICs): a systematic review.BMJ global health · 2022Pooled it
- Hospitalisation costs associated with heart failure with preserved ejection fraction (HFpEF): a systematic review.Heart failure reviews · 2022Pooled it
- The cost of oral cancer: A systematic review.PloS one · 2022Pooled it
- The economic burden of amyotrophic lateral sclerosis: a systematic review.The European journal of health economics : HEPAC : health economics in prevention and care · 2021Pooled it
151 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cost-of-illness (COI) studies aim to assess the economic burden of health problems on the population overall, and they are conducted for an ever widening range of health conditions and geographical settings. While they attract much interest from public health advocates and healthcare policy makers, inconsistencies in the way in which they are conducted and a lack of transparency in reporting have made interpretation difficult, and have ostensibly limited their usefulness. Yet there is surprisingly little in the literature to assist the non-expert in critically evaluating these studies. This article aims to provide non-expert readers with a straightforward guide to understanding and evaluating traditional COI studies. The intention is to equip a general audience with an understanding of the most important issues that influence the validity of a COI study, and the ability to recognize the most common limitations in such work.
Indexed as
Identifiers
21604822What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.