ArticleInternal and emergency medicine2013
High correlation of babA 2-positive strains of Helicobacter pylori with the presence of gastric cancer.
Article in Internal and emergency medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
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Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Association of Helicobacter pylori babA2 gene and gastric cancer risk: a meta-analysis.BMC cancer · 2020Pooled it
- Association of Helicobacter pylori babA2 with peptic ulcer disease and gastric cancer.World journal of gastroenterology · 2013Pooled it
- Comparative Evaluation of Tongue and Periodontal Pocket Microbiome in Relation toAntibiotics (Basel, Switzerland) · 2025Article
- Expression Assessment of theInternational journal of molecular and cellular medicine · 2023Article
- Differences in gastric microbiota and mucosal function between patients with chronic superficial gastritis and intestinal metaplasia.Frontiers in microbiology · 2022Article
- Alterations in the gastric microbiota and metabolites in gastric cancer: An update review.Frontiers in oncology · 2022Review
- Review
- Epidemiologic Study of Gastric Cancer in Iran: A Systematic Review.Clinical and experimental gastroenterology · 2020Review
- Prevalence of theThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2020Article
- The Prevalence of Helicobacter Pylori babA, homB, aspA, and sabA Genes and Its Relationship with Clinical Outcomes in Turkey.Canadian journal of gastroenterology & hepatology · 2019Article
- Role of polymorphisms in genes that encode cytokines and Helicobacter pylori virulence factors in gastric carcinogenesis.World journal of clinical oncology · 2018Review
- Review
- Strategies used byWorld journal of gastroenterology · 2017Review
- Dynamic Expansion and Contraction ofmBio · 2017Article
- Helicobacter pylori bab characterization in clinical isolates from Bhutan, Myanmar, Nepal and Bangladesh.PloS one · 2017Article
- Role ofWorld journal of gastroenterology · 2016Review
- Helicobacter pylori outer membrane protein, HomC, shows geographic dependent polymorphism that is influenced by the Bab family.Journal of microbiology (Seoul, Korea) · 2016Article
- Management of Helicobacter pylori infections.BMC gastroenterology · 2016Article
- Vaccine against Helicobacter pylori: Inevitable approach.World journal of gastroenterology · 2016Review
- Helicobacter pylori vacA i region polymorphism but not babA2 status associated to gastric cancer risk in northwestern Iran.Clinical and experimental medicine · 2016Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Helicobacter pylori (H. pylori) is a Gram-negative bacterium that is well known in the involvement of chronic inflammation in the gastric mucosa of the human stomach. Several studies have investigated the possible role of H. pylori presence in different gastroduodenal disorders with conflicting results. This study aimed to further investigate such a field. Helicobacter pylori strains were cultured from 160 patients (mean age of 42 years; range 15-75; 90 were male, and 70 were female) [40 gastric cancer (GC), 55 duodenal ulcer (DU) and 65 non-ulcer dyspepsia (NUD)]. In this study, allelic variants of iceA 1, iceA 2 and babA 2 were identified by polymerase chain reaction. The overall prevalence of babA 2 gene was 40.6% (65/160). The prevalence of babA 2 gene was 95% with gastric cancer, 18.1% with duodenal ulcer and 26.1% with non ulcer dyspepsia, respectively. The prevalence of babA 2 in GC patients was significantly higher as compared to either NUD or UD patients (P = 0.0004), while no statistical significance was found between the latter two patient groups. Our study finds that babA 2 and iceA 1 genes are more prevalent in GC compared to either NUD or DU patients in Iran.
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