ArticleNeurochemical research2011
Acute restraint stress in zebrafish: behavioral parameters and purinergic signaling.
Article in Neurochemical research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
25 citing papers in PubMed, 64 citations in OpenAlex.
- Differential Adenosine Signaling and Effects of Acute Caffeine Exposure on Alternative Stress Coping Styles in Zebrafish (Danio rerio).Brain and behavior · 2026Article
- Differential adenosine signaling and effects of acute caffeine exposure on alternative stress coping styles in zebrafish (bioRxiv : the preprint server for biology · 2026Article
- Immunoendocrine response to individual or combined exposure of polystyrene nanoplastics and elevated salinity on gilthead seabream.Frontiers in endocrinology · 2026Article
- Synergistic enhancement of detection-tracking framework for zebrafish shoaling behavior analysis.Scientific reports · 2025Article
- Zebrafish as a Model Organism for Post-Traumatic Stress Disorder: Insights into Stress Mechanisms and Behavioral Assays.Biology · 2025Review
- Ascorbic Acid Prevents Efavirenz-Induced Anxiety-Like Behavior and Brain Oxidative Stress in Zebrafish.Oxidative medicine and cellular longevity · 2025Article
- Distinct acute stressors produce different intensity of anxiety-like behavior and differential glutamate release in zebrafish brain.Frontiers in behavioral neuroscience · 2024Article
- Adenosine signaling: a potential therapeutic target for psychogenic erectile dysfunction.American journal of translational research · 2024Review
- Structural environmental enrichment and the way it is offered influence cognitive judgement bias and anxiety-like behaviours in zebrafish.Animal cognition · 2023Article
- Non-micronized and micronized curcumin do not prevent the behavioral and neurochemical effects induced by acute stress in zebrafish.Pharmacological reports : PR · 2022Article
- [A Review of the State of Purinergic Signaling and Psychological Stress].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2021Review
- Acute and chronic stress prevents responses to pain in zebrafish: evidence for stress-induced analgesia.The Journal of experimental biology · 2020Article
- Effects of N-acetylcysteine amide on anxiety and stress behavior in zebrafish.Naunyn-Schmiedeberg's archives of pharmacology · 2020Article
- Putative Activation of the CB1 Cannabinoid Receptors Prevents Anxiety-Like Behavior, Oxidative Stress, and GABA Decrease in the Brain of Zebrafish Submitted to Acute Restraint Stress.Frontiers in behavioral neuroscience · 2020Article
- Handling stress impairs learning through a mechanism involving caspase-1 activation and adenosine signaling.Brain, behavior, and immunity · 2019Article
- The effects of male social environment on sperm phenotype and genome integrity.Journal of evolutionary biology · 2019Article
- Divergent effect of fluoxetine on the response to physical or chemical stressors in zebrafish.PeerJ · 2017Article
- Stress test of a biological early warning system with zebrafish (Danio rerio).Ecotoxicology (London, England) · 2017Article
- Unpredictable Chronic Stress Alters Adenosine Metabolism in Zebrafish Brain.Molecular neurobiology · 2016Article
- Benzodiazepines alter nucleotide and nucleoside hydrolysis in zebrafish (Danio rerio) brain.Journal of neural transmission (Vienna, Austria : 1996) · 2015Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite the extensive knowledge about the effects of acute restraint stress (ARS) in rodents, zebrafish research is still elementary in this field, and the consequences of stress on purinergic system are unclear. Therefore, we evaluated the effects of ARS on behavior, biochemical, and molecular parameters in zebrafish brain. Animals were submitted to a 90 min ARS protocol and tested for anxiety levels, exploratory behavior, and memory performance. Furthermore, we analyzed ectonucleotidase and adenosine deaminase activities and their gene expression profile, as well as transcription of adenosine receptors. ARS increased anxiety, but did not impair locomotion or cognition. ARS significantly increased ATP hydrolysis, decreased cytosolic ADA activity, and changed the entpd and adora gene expression. In conclusion, ARS disturbed zebrafish behavior, and we hypothesize that the augmentation in adenosine-mediated signaling may be a strategy to reestablish homeostasis and normal behavior after a stressful event.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.