ArticleMarine biotechnology (New York, N.Y.)2012
Transcriptomic analysis of the clam Meretrix meretrix on different larval stages.
Article in Marine biotechnology (New York, N.Y.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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41 citing papers in PubMed, 99 citations in OpenAlex.
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- Larval development in the Pacific oyster and the impacts of ocean acidification: Differential genetic effects in wild and domesticated stocks.Evolutionary applications · 2021Article
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- Integrated mRNA and Small RNA Sequencing Reveals Regulatory Expression of Larval Metamorphosis of the Razor Clam.Marine biotechnology (New York, N.Y.) · 2020Article
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- Effects of a Sudden Drop in Salinity on Immune Response Mechanisms ofInternational journal of molecular sciences · 2019Article
- FunctionAnnotator, a versatile and efficient web tool for non-model organism annotation.Scientific reports · 2017Article
- Developmental piRNA profiles of the invasive vector mosquito Aedes albopictus.Parasites & vectors · 2016Article
- Developmental Transcriptome Analysis and Identification of Genes Involved in Larval Metamorphosis of the Razor Clam, Sinonovacula constricta.Marine biotechnology (New York, N.Y.) · 2016Article
- Differential Gene Expression during Larval Metamorphic Development in the Pearl Oyster,International journal of genomics · 2016Article
- Transcriptome Analysis of the Sydney Rock Oyster, Saccostrea glomerata: Insights into Molluscan Immunity.PloS one · 2016Article
- Heterosis and differential gene expression in hybrids and parents in Bombyx mori by digital gene expression profiling.Scientific reports · 2015Article
- Transcriptome analysis of eyestalk and hemocytes in the ridgetail white prawn Exopalaemon carinicauda: assembly, annotation and marker discovery.Molecular biology reports · 2015Article
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The clam Meretrix meretrix (Mollusca: Bivalvia) is an important commercial species in China. The deficiency of genomic and transcriptomic data is becoming the bottleneck of further researches on its complex and unique developmental processes. To improve this situation, in this study, a large-scale RNA sequencing was conducted on M. meretrix on larval stages. In particular, mRNAs of trochophore, D-veliger, pediveliger, and postlarva were purified, reverse transcribed, and sequenced through 454 sequencing technology. A total of 704,671 reads were obtained and assembled into 124,737 unique sequences (35,205 contigs and 89,532 singletons). Further analysis showed that 118,075 (94.66%) of these sequences were low-expression-level transcripts. Fifteen thousand two hundred fifteen (12.20%) of the unique sequences were annotated by searching against Uniprot Protein Knowledgebase, while the others (109,522, 87.80%) were left as novel sequences. Gene ontology analysis of the annotated sequences showed that most of them were assigned to certain gene ontology terms. By analyzing the depth of each unique sequence, a preliminary quantification analysis was conducted. An amount of sequences that showed a dramatic transcript discrepancy among the four larval stages were screened, which were related to development, growth, shell formation, and immune responses etc. As the first attempt on large-scale RNA sequencing of marine bivalve larvae, this work would enrich the knowledge of larval development of marine bivalves and provide fundamental support for further researches.
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