ArticleChromosoma1990
Two puff-specific proteins bind within the 2.5 kb upstream region of the Drosophila melanogaster Sgs-4 gene.
Article in Chromosoma, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 33 citations in OpenAlex.
- Mutations in the spliceosomal gene SNW1 cause neurodevelopment disorders with microcephaly.The Journal of clinical investigation · 2025Article
- SKIP is a component of the spliceosome linking alternative splicing and the circadian clock in Arabidopsis.The Plant cell · 2012Article
- A homolog of human ski-interacting protein in rice positively regulates cell viability and stress tolerance.Proceedings of the National Academy of Sciences of the United States of America · 2009Article
- The Drosophila insulator proteins CTCF and CP190 link enhancer blocking to body patterning.The EMBO journal · 2007Article
- SKIP is an indispensable factor for Caenorhabditis elegans development.Proceedings of the National Academy of Sciences of the United States of America · 2002Article
- Ski interacts with the evolutionarily conserved SNW domain of Skip.Nucleic acids research · 2001Article
- The fork head product directly specifies the tissue-specific hormone responsiveness of the Drosophila Sgs-4 gene.The EMBO journal · 1996Article
- Ecdysone regulation of the Drosophila Sgs-4 gene is mediated by the synergistic action of ecdysone receptor and SEBP 3.The EMBO journal · 1995Article
- The enhancer of position-effect variegation of Drosophila, E(var)3-93D, codes for a chromatin protein containing a conserved domain common to several transcriptional regulators.Proceedings of the National Academy of Sciences of the United States of America · 1993Article
- The Rb97D gene encodes a potential RNA-binding protein required for spermatogenesis in Drosophila.Nucleic acids research · 1993Article
- A model for chromatin opening: stimulation of topoisomerase II and restriction enzyme cleavage of chromatin by distamycin.The EMBO journal · 1993Article
- The Drosophila nuclear protein Bx42, which is found in many puffs on polytene chromosomes, is highly charged.Chromosoma · 1992Article
- The puff-specific Drosophila protein Bj6, encoded by the gene no-on transient A, shows homology to RNA-binding proteins.Chromosoma · 1990Article
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Drosophila nuclear proteins Bj6 and Bx42 characterized previously are detected in a series of developmentally active puffs on salivary gland chromosomes. Here the binding of both proteins at puff 3C11-12 containing the glue protein gene Sgs-4 is described in more detail. By deletion analysis we show that both proteins bind within a chromosomal segment containing 17-19 kb of DNA surrounding the Sgs-4 gene. They are detectable at this site during the intermoult stages, before the puff regresses in response to the moulting hormone ecdysone. If the Sgs-4 gene together with flanking DNA sequences is brought into a different chromosomal position by P element transfer, both proteins are detected at this new location. Both proteins are bound to the chromosome within the range of 2.5 kb DNA upstream of the Sgs-4 gene. A strain containing a 52 bp deletion within this region fails to bind Bx42 protein suggesting that the missing DNA, which overlaps a hypersensitive region, may be required for the binding of the Bx42 protein.
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