Evidence map›Paper›PMID 21603320›Full record

ArticleWorld journal of clinical oncology2011

Glucan-immunostimulant, adjuvant, potential drug.

Vaclav Vetvicka

Abstract read
In one paragraph

Article in World journal of clinical oncology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Effects of β-Glucan Supplementation on LPS-Induced Endotoxemia in Horses.Animals : an open access journal from MDPI · 2024
    Article
  6. Review
  7. Glucans: A Therapeutic Alternative for Sepsis Treatment.Journal of immunology research · 2024
    Review
  8. Article
  9. Potent induction of trained immunity byFrontiers in immunology · 2024
    Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. A new insight in immunomodulatory impact of botanicals in treating avian coccidiosis.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2022
    Review
  17. Review
  18. Developments in Vaccine Adjuvants.Methods in molecular biology (Clifton, N.J.) · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Vaclav VetvickaVaclav Vetvicka, Department of Pathology, University of Louisville, Louisville, KY 40202, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

β-glucans belong to a group of biologically active natural compounds called biological response modifiers. These substances represent highly conserved structural components of cell walls in fungi, yeast, grain and seaweed. Despite almost 160 years of intensive research, the exact mechanisms of their action remain unsolved. The significant role of glucans in cancer treatment, infection immunity, stress reduction and restoration of damaged bone marrow has already been established. The present review focuses on the various less known but potentially significant roles glucans might play in medicine. In summary, glucan might represent the most important natural immunomodulator.

Indexed as

Biological Response ModifiersCancerCR3GlucanImmunityImmunomodulatorsResveratrol

Identifiers

PMID21603320
PMCPMC3095473

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.