ArticleEnzyme research2011
Phospholipases a in trypanosomatids.
Article in Enzyme research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 26 citations in OpenAlex.
- Overproduction and Characterization of Recombinant SolubleEngineering in life sciences · 2025Article
- Phospholipids and phospholipase A1 as antigens during the course of experimental Trypanosoma cruzi infection.Memorias do Instituto Oswaldo Cruz · 2025Article
- State-of-the-Art in the Drug Discovery Pathway for Chagas Disease: A Framework for Drug Development and Target Validation.Research and reports in tropical medicine · 2023Review
- Antileishmanial effects of γCdcPLI, a phospholipase A2 inhibitor from Crotalus durissus collilineatus snake serum, on Leishmania (Leishmania) amazonensis.Memorias do Instituto Oswaldo Cruz · 2023Article
- Article
- A novel lipase with dual localisation in Trypanosoma brucei.Scientific reports · 2022Article
- Endocytosis and Exocytosis inFrontiers in cellular and infection microbiology · 2020Article
- Gluconeogenesis is essential for trypanosome development in the tsetse fly vector.PLoS pathogens · 2018Article
- Effect of phospholipase AThe journal of venomous animals and toxins including tropical diseases · 2018Article
- Lipids FromFrontiers in cellular and infection microbiology · 2018Article
- Structural and functional analysis of a platelet-activating lysophosphatidylcholine of Trypanosoma cruzi.PLoS neglected tropical diseases · 2014Article
- Leishmania parasites possess a platelet-activating factor acetylhydrolase important for virulence.Molecular and biochemical parasitology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Phospholipases are a complex and important group of enzymes widespread in nature, that play crucial roles in diverse biochemical processes and are classified as A(1), A(2), C, and D. Phospholipases A(1) and A(2) activities have been linked to pathogenesis in various microorganisms, and particularly in pathogenic protozoa they have been implicated in cell invasion. Kinetoplastids are a group of flagellated protozoa, including extra- and intracellular parasites that cause severe disease in humans and animals. In the present paper, we will mainly focus on the three most important kinetoplastid human pathogens, Trypanosoma brucei, Trypanosoma cruzi, and Leishmania spp., giving a perspective of the research done up to now regarding biochemical, biological, and molecular characteristics of Phospholipases A(1) and A(2) and their contribution to pathogenesis.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.