ArticleInternational journal of pediatric endocrinology2011
Gonadotropin-dependent precocious puberty: neoplastic causes and endocrine considerations.
Article in International journal of pediatric endocrinology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.
- The Effect of GnRHa Treatment on Body Mass Index in Central Precocious Puberty: A Systematic Review and Meta-Analysis.Hormone research in paediatrics · 2024Pooled it
- MRI features and radiomics of the pineal gland in girls do not show significant changes at onset of puberty.Frontiers in endocrinology · 2026Article
- Bioinformatics analysis explores key pathways and hub genes in central precocious puberty.Journal of pediatric endocrinology & metabolism : JPEM · 2025Article
- Magnetic resonance imaging -based radiomics of the pituitary gland is highly predictive of precocious puberty in girls: a pilot study.Frontiers in endocrinology · 2025Article
- BifocalCase reports in pediatrics · 2025Article
- Article
- Congenital Portosystemic Shunts: Variable Clinical Presentations Requiring a Tailored Endovascular or Surgical Approach.JPGN reports · 2023Review
- Incidental pineal gland cyst in girls with early onset of puberty.Italian journal of pediatrics · 2022Article
- A Rare Case of Posterior Fossa Tumor and Central Precocious Puberty: Case Presentation and Review of the Literature.Neurology international · 2021Article
- Diagnosis and management of precocious sexual maturation: an updated review.European journal of pediatrics · 2021Review
- [Clinical guidelines «Precocious puberty»].Problemy endokrinologii · 2021Article
- The Effects of Negative Elements in Environment and Cancer on Female Reproductive System.Advances in experimental medicine and biology · 2021Article
- Coincidental Central Precocious Puberty and Wilms Tumor in a 5-Year-Old Girl.Case reports in pediatrics · 2019Article
- Etiological trends in male central precocious puberty.Annals of pediatric endocrinology & metabolism · 2018Article
- Review
- Precocious puberty: An experience from a major teaching hospital in Central Saudi Arabia.Sudanese journal of paediatrics · 2017Article
- Endocrine and pubertal disturbances in optic nerve hypoplasia, from infancy to adolescence.International journal of pediatric endocrinology · 2015Article
- Extensive middle cranial fossa arachnoid cysts and different clinical presentation in two patients.Journal of clinical research in pediatric endocrinology · 2014Article
- Neoplastic causes of abnormal puberty.Pediatric blood & cancer · 2014Article
- Endocrinopathies in survivors of childhood neoplasia.Frontiers in pediatrics · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Premature activation of the hypothalamic-pituitary-gonadal (HPG) axis manifests as gonadotropin-dependent precocious puberty. The mechanisms behind HPG activation are complex and a clear etiology for early activation is often not elucidated. Though collectively uncommon, the neoplastic and developmental causes of gonadotropin-dependent precocious puberty are very important to consider, as a delay in diagnosis may lead to adverse patient outcomes. The intent of the current paper is to review the neoplastic and developmental causes of gonadotropin-dependent precocious puberty. We discuss the common CNS lesions and human chorionic gonadotropin-secreting tumors that cause sexual precocity, review the relationship between therapeutic radiation and gonadotropin-dependent precocious puberty, and finally, provide an overview of the therapies available for height preservation in this unique patient population.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.