Evidence map›Paper›PMID 21603174›Full record

ArticleStroke research and treatment2011

Barriers of thrombolysis therapy in developing countries.

Kavian Ghandehari

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Stroke research and treatment, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Time delays in emergency stroke care in a low-resource referral hospital in Ghana.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2025
    Article
  5. Article
  6. Observational
  7. Observational
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Stumbling Blocks to Stroke Thrombolysis: An Indian Perspective.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2023
    Article
  14. Review
  15. Biomarkers of Stroke: Its Utility in Routine Clinical Practice.Journal of neurosciences in rural practice · 2022
    Article
  16. Childhood stroke.Nature reviews. Disease primers · 2022
    Review
  17. Article
  18. Observational
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Kavian GhandehariNeuroscience Research Center, Mashhad University of Medical Sciences, Mashhad, P.O. Box: 91766-99199, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The developing world carries the highest burden of stroke mortality and stroke-related disability. The number of stroke patients receiving r-tPA in the developing world is extremely low. Prehospital delay, financial constraints, and lack of infrastructure are main barriers of thrombolysis therapy in developing countries. Until a cheaper thrombolytic agent and the proper infrastructure for utilization of thrombolytic therapy is available, developing countries should focus on primary and secondary stroke prevention strategies. However, governments and health systems of developing countries should efforts exerb for promotion of their infrastructure of stroke care.

Identifiers

PMID21603174
PMCPMC3095908

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.