ArticleInternational journal of nephrology2011
Cardiorenal syndromes and sepsis.
Article in International journal of nephrology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 22 citations in OpenAlex.
- Multimorbidity patterns and outcomes among adults (non-maternity) with community-onset sepsis in Ireland: a retrospective national analysis of acute hospital data, 2020-2025.Irish journal of medical science · 2026Article
- Decoding cardiorenal crosstalk: Intercellular communication mechanisms and therapeutic insights in cardiorenal syndrome.iScience · 2026Review
- Article
- Troponin Testing for Assessing Sepsis-Induced Myocardial Dysfunction in Patients with Septic Shock.Journal of clinical medicine · 2019Article
- Edaravone Improves Septic Cardiac Function by Inducing an HIF-1Oxidative medicine and cellular longevity · 2018Article
- The Role of Endotoxin in the Setting of Cardiorenal Syndrome Type 5.Cardiorenal medicine · 2017Review
- Role of Admission Troponin-T and Serial Troponin-T Testing in Predicting Outcomes in Severe Sepsis and Septic Shock.Journal of the American Heart Association · 2017Article
- Influenza Vaccination Reduces Hospitalization for Heart Failure in Elderly Patients with Chronic Kidney Disease: A Population-Based Cohort Study.Acta Cardiologica Sinica · 2016Article
- Cellular apoptosis in the cardiorenal axis.Heart failure reviews · 2016Review
- Extracorporeal Membrane Oxygenation and the Kidney.Cardiorenal medicine · 2015Article
- Glycocalyx and sepsis-induced alterations in vascular permeability.Critical care (London, England) · 2015Article
- Heart-kidney crosstalk and role of humoral signaling in critical illness.Critical care (London, England) · 2014Review
- Complexity science to conceptualize health and disease: is it relevant to clinical medicine?Mayo Clinic proceedings · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The cardiorenal syndrome is a clinical and pathophysiological entity defined as the concomitant presence of renal and cardiovascular dysfunction. In patients with severe sepsis and septic shock, acute cardiovascular, and renal derangements are common, that is, the septic cardiorenal syndrome. The aim of this paper is to describe the pathophysiology and clinical features of septic cardiorenal syndrome in light of the actual clinical and experimental evidence. In particular, the importance of systemic and intrarenal endothelial dysfunction, alterations of kidney perfusion, and myocardial function, organ "crosstalk" and ubiquitous inflammatory injury have been extensively reviewed in light of their role in cardiorenal syndrome etiology. Treatment includes early and targeted optimization of hemodynamics to reverse systemic hypotension and restore urinary output. In case of persistent renal impairment, renal replacement therapy may be used to remove cytokines and restore renal function.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.