ArticleJournal of neurogastroenterology and motility2011
Noncardiac chest pain: epidemiology, natural course and pathogenesis.
Article in Journal of neurogastroenterology and motility, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05402462 (Esophageal Motility Disorders in Patients With Non-cardiac Chest Pain at Assiut University Hospital), which is not on this map. Cited by 75 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Esophageal Motility Disorders in Patients With Non-cardiac Chest Pain at Assiut University Hospital
Who cites it
75 citing papers in PubMed, 189 citations in OpenAlex.
- Effect of Diaphragmatic Breathing Exercise, Jacobson's Relaxation Technique and Dynamic Neuromuscular Stabilization on Gastrointestinal and Psychological Causes of Noncardiac Chest Pain: A Randomized Controlled Trial.Pain research & management · 2025Trial
- Circumferential Heller myotomy can relieve chest pain in patients with achalasia: a prospective clinical trial.Esophagus : official journal of the Japan Esophageal Society · 2020Trial
- [Therapeutic Response to 20 mg of Esomeprazole Twice Daily in Patients with Gastroesophageal Reflux Disease-related Non-cardiac Chest Pain: An Open-Label Randomized Pilot Study].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2020Trial
- Evaluation of alexithymia, somatosensory sensitivity, and health anxiety levels in patients with noncardiac chest pain.BioMed research international · 2014Trial
- Article
- Functional Dysphagia Presenting With Severe Subjective Swallowing Difficulty Despite Minimal Objective Findings: A Case Report.Case reports in otolaryngology · 2026Article
- Before the diagnosis: quality of life in patients presenting with chest pain undergoing Bruce protocol stress testing.BMC cardiovascular disorders · 2025Article
- Article
- Determinants of severity of pain in non-cardiac chest pain patients: A cross sectional study.ARYA atherosclerosis · 2025Article
- Predictive Factors and Risk Assessment for Hospitalization in Chest Pain Patients Admitted to the Emergency Department.Diagnostics (Basel, Switzerland) · 2024Article
- The Role of Psychological Factors in Noncardiac Chest Pain of Esophageal Origin.Journal of neurogastroenterology and motility · 2024Review
- Article
- Latin American consensus on diagnosis of gastroesophageal reflux disease.Neurogastroenterology and motility · 2024Article
- Biobehavioral approach to distinguishing panic symptoms from medical illness.Frontiers in psychiatry · 2024Review
- Non-cardiac Chest Pain in Japan: Prevalence, Impact, and Consultation Behavior - A Population-based Study.Journal of neurogastroenterology and motility · 2023Article
- Effectiveness of a training program for a patient with non-cardiac chest pain that combines intervention to improve quality of life, psychological state, and functional capacity: a case report.BioPsychoSocial medicine · 2023Article
- Predictors of long-term symptom burden and quality of life in patients hospitalised with chest pain: a prospective observational study.BMJ open · 2022Observational
- There is little association between prehospital delay, persistent symptoms, and post-discharge healthcare utilization in patients evaluated for acute coronary syndrome.Applied nursing research : ANR · 2022Article
- Neural signalling of gut mechanosensation in ingestive and digestive processes.Nature reviews. Neuroscience · 2022Review
- Effectiveness of Nutritional Ingredients on Upper Gastrointestinal Conditions and Symptoms: A Narrative Review.Nutrients · 2022Review
15 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Noncardiac chest pain is defined as recurrent chest pain that is indistinguishable from ischemic heart pain after a reasonable workup has excluded a cardiac cause. Noncardiac chest pain is a prevalent disorder resulting in high healthcare utilization and significant work absenteeism. However, despite its chronic nature, noncardiac chest pain has no impact on patients' mortality. The main underlying mechanisms include gastroesophageal reflux, esophageal dysmotility and esophageal hypersensitivity. Gastroesophageal reflux disease is likely the most common cause of noncardiac chest pain. Esophageal dysmotility affects only the minority of noncardiac chest pain patients. Esophageal hypersensitivity may be present in non-GERD-related noncardiac chest pain patients regardless if esophageal dysmotility is present or absent. Psychological co-morbidities such as panic disorder, anxiety, and depression are also common in noncardiac chest pain patients and often modulate patients' perception of disease severity.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.