Evidence map›Paper›PMID 21602906›Full record

ArticleNature reviews. Molecular cell biology2011

Keeping mRNPs in check during assembly and nuclear export.

Evelina Tutucci, Françoise Stutz

Abstract read
PubMed Publisher
In one paragraph

Article in Nature reviews. Molecular cell biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed.

  1. Article
  2. Review
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  5. Review
  6. Article
  7. Review
  8. Article
  9. Measuring Repeat-Associated Non-AUG (RAN) Translation.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Evelina TutucciDepartment of Cell Biology and "Frontiers in Genetics", National Center for Competence in Research (NCCR), Sciences III, Geneva, Switzerland.
Françoise Stutz

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cell nucleus is an intricate organelle that coordinates multiple activities that are associated with DNA replication and gene expression. In all eukaryotes, it stores the genetic information and the machineries that control the production of mature and export-competent messenger ribonucleoproteins (mRNPs), a multistep process that is regulated in a spatial and temporal manner. Recent studies suggest that post-translational modifications play a part in coordinating the co-transcriptional assembly, remodelling and export of mRNP complexes through nuclear pores, adding a new level of regulation to the process of gene expression.

Indexed as

Active Transport, Cell NucleusCell NucleusDNA ReplicationGene ExpressionGene Expression RegulationHumansNuclear Matrix-Associated ProteinsNuclear PoreNucleocytoplasmic Transport ProteinsProtein Processing, Post-TranslationalRibonucleoproteinsRNA Polymerase IISaccharomyces cerevisiaemessenger ribonucleoproteinNuclear Matrix-Associated ProteinsNucleocytoplasmic Transport ProteinsRibonucleoproteinsRNA Polymerase II

Identifiers

PMID21602906

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.